CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017638
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Maestro heat-like repeat-containing protein family member 1 
Protein Synonyms/Alias
 HEAT repeat-containing protein 7A 
Gene Name
 MROH1 
Gene Synonyms/Alias
 HEATR7A; KIAA1833 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1082RGGVLQEKVPEIVSVubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661
Functional Description
  
Sequence Annotation
 REPEAT 3 41 HEAT 1.
 REPEAT 159 198 HEAT 2.
 REPEAT 344 382 HEAT 3.
 REPEAT 385 423 HEAT 4.
 REPEAT 1048 1086 HEAT 5.
 REPEAT 1358 1396 HEAT 6.
 REPEAT 1605 1641 HEAT 7.  
Keyword
 Alternative splicing; Complete proteome; Polymorphism; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1641 AA 
Protein Sequence
MTESSMKKLA STLLDAITDK DPLVQEQVCS ALCSLGEARP VETLRACEEY LRQHDKLAHP 60
YRAAVLRAME RVLSSRASEL DKDTASTIIL LASSEMTKTK DLVWDWQQAA SGVLVAVGRQ 120
FISKVMEELL RRLHPGTLPH CAVLHTLASL SVANAFGVVP FLPSVLSSLL PVLGVAKQDT 180
VRVAFCSALQ RFSEGALEYL ANLDRAPDPT VRKDAFATDI FSAYDVLFHQ WLQSREAKLR 240
LAVVEALGPM SHLLPSERLE EQLPKLLPGI LALYKKHAET FYLSKSLGQI LEAAVSVGSR 300
TLETQLDALL AALHSQICVP VESSSPLVMS NQKEVLRCFT VLACSSPDRL LAFLLPRLDT 360
SNERTRVGTL QVVRHVINSA AAQMEDKKPF ILSSMRLPLL DTNSKVKRAV VQVISAMAHH 420
GYLEQPGGEA MIEYIVQQCA LPPEQEPEKP GPGSKDPKAD SVRAISVRTL YLVSTTVDRM 480
SHVLWPYLLQ FLTPVRFTGA LTPLCRSLVH LAQKRQEAGA DAFLIQYDAH ASLPSPYAVT 540
GRLLVVSSSP YLGDGRGAAA LRLLSVLHPN IHPLLGQHWE TTVPLLLGYL DEHTEETLPQ 600
EEWEEKLLMF LRDTLAIISD NAWICQLSLE LCRQLPCYDE APQEKNFLYK CIGTTLGAAS 660
SKEVVRKHLQ ELLETARYQE EAEREGLACC FGICAISHLE DTLAQLEDFV RSEVFRKSIG 720
ILNIFKDRSE NEVEKVKSAL ILCYGHVAAR APRELVLAKV ESDILRNICQ HFSTKDPALK 780
LCLVQSVCMV SRAICSSTQA GSFHFTRKAE LVAQMMEFIR AEPPDSLRTP IRKKAMLTCT 840
YLVSVEPALD EQARADVIHG CLHSIMALLP EPKEEDGGCQ KSLYLETLHA LEDLLTSLLQ 900
RNMTPQGLQI MIEHLSPWIK SPRGHERARA LGLSALLLRY FLEHLRVSAL VPFHNLGLLI 960
GLFSPRCADL WPATRQEAVD CVYSLLYLQL GYEGFSRDYR DDVAERLLSL KDGLVHPDPA 1020
ILFHTCHSVG QIIAKRLPPD QLISLLLTMF EALGDPEKNC SRAATVMINC LLQERGGVLQ 1080
EKVPEIVSVL RSKLQEAQGE HVLPAAQHSV YLLATQHCAA VVSSLLGSPL PLDRYPAQTP 1140
GLGVPLE 1147 
Gene Ontology
  
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR000357; HEAT.
 IPR021133; HEAT_type_2. 
Pfam
 PF02985; HEAT 
SMART
  
PROSITE
 PS50077; HEAT_REPEAT 
PRINTS