CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024861
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 T-complex protein 1, putative 
Protein Synonyms/Alias
  
Gene Name
 PFB0635w 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
317MTLKITSKFETLRICacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Chaperone; Complete proteome; Cytoplasm; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 542 AA 
Protein Sequence
MFSNKLGVNS ILKDGYRIMK NNEDTILKNI EACKEICNIL QTSLGPKCMN KLIINHIHKK 60
IVSSDCITIL NDMEINHPVV NILKKLSETI NYEYGDFTNY AFTITCEILD KASFLIQQGF 120
NINDILNGFV LGYKEIEKVL EEMIVWKVPN FYEEKELIKV LKSVMLTKNI SNNYNFLIQL 180
LAKCISTLMP EKIEDFDVDN IRVSKLNGGN IIDSEFLMGM VIAREANGII KKKENANVIV 240
LNCGLEGPTT ETKGTVLLHN AEELINYTKG EELQMKKYID NFKKANVDVI IVNGAISDIA 300
QHFCDTNNIM TLKITSKFET LRICKLLNIS SLIKLSTPQP EDIGKVSSIY VSEIASKKVT 360
IINSKNKKVG TIILRGATFN LLDEVERCIH DGINSIKNAI KGNAFLHGGG CVEIQLCLAL 420
KKYANQLKGV DNYCVKIFAE AFYIIPKILA RNAGYNTTDV LNELINEHNK GNTHSCININ 480
KDSHITSAQN NHIYDNYNCK KYAIHLAMEA VQTILKIDQI IMSKPAGGPK PRDKNPDYDE 540
AF 542 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0042623; F:ATPase activity, coupled; ISS:GeneDB_Pfalciparum.
 GO:0006457; P:protein folding; IEA:InterPro. 
Interpro
 IPR012721; Chap_CCT_theta.
 IPR017998; Chaperone_TCP-1.
 IPR002423; Cpn60/TCP-1.
 IPR027409; GroEL-like_apical_dom.
 IPR027413; GROEL-like_equatorial.
 IPR027410; TCP-1-like_intermed. 
Pfam
 PF00118; Cpn60_TCP1 
SMART
  
PROSITE
  
PRINTS
 PR00304; TCOMPLEXTCP1.