CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041065
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Solute carrier family 12 member 4 
Protein Synonyms/Alias
  
Gene Name
 Slc12a4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
894DDNSIQMKKDLAIFLubiquitination[1]
990QMTWTRDKYMAEPWDubiquitination[1]
1012FRELVHIKPDQSNVRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1087 AA 
Protein Sequence
MPHFTVVPVD GPRRGDYDNL EGLSWVDYGE RAEREDSDGE GQGNHRENSP FLCPLDASRG 60
NDYYDRNLAL FEEELDIRPK VSSLLGKLVS YTNLTQGAKE HEEAESGEGG RRRAAKAPSM 120
GTLMGVYLPC LQNIFGVILF LRLTWMVGTA GVLQALLIVL ICCCCTLLTA ISMSAIATNG 180
VVPAGGSYFM ISRSLGPEFG GAVGLCFYLG TTFAAAMYIL GAIEILLTYI APPAAIFYPS 240
GTHDMSSATL NNMRVYGTIF LTLMTLVVFV GVKYVNKFAS LFLACVIISI LSIYAGGIKS 300
IFDPPVFPVC MLGNRTLSRD QFDICAKTVV VDNETVATRL WTFFCHSPNL TADSCDPYFL 360
LNNVTEIPGI PGAAAGVLQE NLWSAYLEKG EVVEKHGLPS TDTLGLKESL SLYVVADIAT 420
SFTVLVGIFF PSVTGIMAGS NRSGDLRDAQ KSIPVGTILA IVTTSLVYFS SVILFGACIE 480
GVVLRDKYGD GVSRNLVVGT LAWPSPWVIV VGSFFSTCGA GLQSLTGAPR LLQAIAKDNI 540
IPFLRVFGHG KANGEPTWAL LLTALIAELG ILIASLDMVA PILSMFFLMC YLFVNLACAV 600
QTLLRTPNWR PRFKYYHWTL SFLGMSLCLA LMFVSSWYYA LVAMLIAGMI YKYIEYQGAE 660
KEWGDGIRGL SLSAARYALL RLEEGPPHTK NWRPQLLVLL KLDEDLHVKY PRLLTFASQL 720
KAGKGLTIVG SVIQGSFLES YGEAQAAEQT IKNMMDIEKV KGFCQVVVAS KVREGLAHLI 780
QSCGLGGMRH NSVVLGWPYG WRQSEDPRAW KTFIDTVRCT TAAHLALLVP KNIAFYPSNH 840
ERYLDGHIDV WWIVHDGGML MLLPFLLRQH KVWKKCRMRI FTVAQMDDNS IQMKKDLAIF 900
LYHLRLEAEV EVVEMHNSDI SAYTYERTLM MEQRSQMLRQ MRLTKTERDR EAQLVKDRHS 960
ALRLESLYSD EEEESVAGAD KIQMTWTRDK YMAEPWDPSH APDNFRELVH IKPDQSNVRR 1020
MHTAVKLNEV IVTRSHDARL VLLNMPGPPK NSEGDENYME FLEVLTEGLE RVLLVRGGGR 1080
EVITIYS 1087 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0015379; F:potassium:chloride symporter activity; IEA:InterPro. 
Interpro
 IPR004841; AA-permease_dom.
 IPR000622; K/Cl_cotranspt1.
 IPR018491; K/Cl_cotranspt_1/3.
 IPR000076; KCL_cotranspt.
 IPR004842; Na/K/Cl_cotransptS. 
Pfam
 PF00324; AA_permease
 PF03522; KCl_Cotrans_1 
SMART
  
PROSITE
  
PRINTS
 PR01081; KCLTRNSPORT.
 PR01082; KCLTRNSPORT1.