CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028287
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 PAK2 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
108LQTSNITKLEQKKNPubiquitination[1]
517LLQHPFLKLAKPLSSubiquitination[1]
Reference
 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Kinase; Nucleotide-binding; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 540 AA 
Protein Sequence
MSDGLDNEEK PPAPPLRMNS TPGFFSTQPQ LLPLPMAPEE KNKKARLRSI FPGGGDKTNK 60
KKEKERPEIS LPSDFEHTIH VGFDAVTGEF TGIPEQWARL LQTSNITKLE QKKNPQAVLD 120
VLKFYDSKET VNNQKYMSFT SGDKSAHGYI AAHPSSTKTA SEPPLAPPVS EEEDEEEEEE 180
DENEPPPVIA PRPEHTKSIY TRSVVESIAS PAVPNKEVTP PSAENANSST LYRNTDRQRK 240
KSKMTDEEIL EKLRSIVSVG TQRKNTQFEK IGQGPIRHRY TAMDVATGQE VAIKQMNLQQ 300
QPKKELNINE ILVMRENKNP NIVNYLDSYL VGDELWVVME YLAGGSLTDV VTETCMDEGQ 360
IAAVCRECLQ ALEFLHSNQV IHRDIKSDNI LLGMDGSVKL TDFGFCAQIT PEQSKRSTMV 420
GTPYWMAPEV VTRKAYGPKV DIWSLGIMAI EMVEGEPPYL NENPLRALYL IATNGTPELQ 480
NPEKLSPIFR DFLNRCLEMD VEKRGSAKEL LQHPFLKLAK PLSSLTPLIM AAKEAMKSNR 540 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000095; PAK_box_Rho-bd.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom.
 IPR008271; Ser/Thr_kinase_AS. 
Pfam
 PF00786; PBD
 PF00069; Pkinase 
SMART
 SM00285; PBD
 SM00220; S_TKc 
PROSITE
 PS50108; CRIB
 PS50011; PROTEIN_KINASE_DOM
 PS00108; PROTEIN_KINASE_ST 
PRINTS