UniProt Accession

 PGP_HUMAN; A6NDG6 

Genbank Protein ID

 AC009065; CH471112 

Genbank Nucleotide ID

 EAW85534.1 

Protein Name

 Phosphoglycolate phosphatase 

Protein Synonyms/Alias

 PGP; PGPase 

Gene Name

 PGP 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
72	FITNNSSKTRAAYAE	ubiquitination	[1]
80	TRAAYAEKLRRLGFG	ubiquitination	[1]
183	FSYMKLTKALRYLQQ	ubiquitination	[1]
235	RQADIIGKPSRFIFD	ubiquitination	[1]
290	VSTLGDVKNNQESDC	ubiquitination	[2]
300	QESDCVSKKKMVPDF	acetylation	[3]
301	ESDCVSKKKMVPDFY	ubiquitination	[1]
302	SDCVSKKKMVPDFYV	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

 ACT_SITE 29 29 Nucleophile (By similarity).  

Keyword

 Carbohydrate metabolism; Complete proteome; Hydrolase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 321 AA 

Protein Sequence

Gene Ontology

 GO:0008967; F:phosphoglycolate phosphatase activity; IEA:EC.
 GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-KW.
 GO:0016311; P:dephosphorylation; IEA:GOC. 

Interpro

 IPR023214; HAD-like_dom.
 IPR006357; HAD-SF_hydro_IIA.
 IPR023215; NPhePase-like_dom.
 IPR006349; PGP_euk. 

Pfam

 PF13344; Hydrolase_6 

SMART

  

PROSITE

  

PRINTS