CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034982
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ral GTPase-activating protein subunit alpha-2 
Protein Synonyms/Alias
  
Gene Name
 Ralgapa2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1623RKNFHLLKKNSKLLRacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1870 AA 
Protein Sequence
MFSRRSHGDV KKSTQKVLDP KKDVLTRLKH LRALLDNVDA SDLKQFFETN YSQIYFIFYE 60
NFITLENSLK LKGNNKSQRE ELDSILFLFE KILQFLPERI FFRWHYQSIG STLKKLLHTG 120
NSIKIRCEGI RLFLLWLQAL QTNCAEEQVL IFACLVPGFP AVLSSRGPCT LETLINPSPS 180
VVDAKIYPEE ITPLLPAVSG EKIAEDQTCF FLQILLKYMV IQAASLEWKN KENQDTGFKF 240
LFTLFRKYYL PHLFPSFTKL TNIYKPVLEI PHLRPKPLYV TVTRDNETIY STKIPYMAAR 300
VVFIKWIVTF FLEKKYLTAT QNTKNGVDVL PKIIQTVGGG AIQEKVPELD GAGATEQDKS 360
HSNSSTLSDR RLSNSSLCSI EEEHRTVYEM VQRILLSTRG YVNFVNEVFR QAFLLPSCEI 420
SITRKVVQVK WILQNKPVFM EEPDKKDVAE EDADKLGLSE TDSKEVSSES SGHKRSSSWG 480
RTYSFTSAMS RGCVTEEDNT NVKAGAQAML QVFLTNAANV FLLEPCVEVP MLLREQVDAC 540
KAVLIIFRRM IMELTMNQKT WEQMLQILLR ITEAVMQKPK DKLVQDSFAR SLAGLLFRTL 600
IVAWIRANLC VYISRELWDD FLRVLSSLTE WEELITEWSN IMDSLTAVLA RTVYGVEMTN 660
LPLDKLSEQK EKKQRGKGCV LEPQKGTAVG RSFSLSWRSH PDVTEPMRFR SATTSGAPGV 720
EKARNTVRQK ATEVEEFQQA ESTAAADCDY LVVGQQPVPR SSSTSDITER LYSDSSQGQK 780
VENSQNLSSS EPKSVQESKG HVTHEHEGVT ILVRRSSSPA ELDLKEESQQ THGRCRERQK 840
SESTGSDMAV GYSNEAELPV SPWQTCEEDP ELSTPTDAVA DSDARHWLQL SPTDASNLTE 900
SRECLADDCS IIAGGNLTGW HPDSAAVLWR RVLGILGDVN NIQSPKIHAK VFSYLYELWY 960
KLAKIRDNLA ISLDNQSSPS PPLLIPPLRM FASWLFKATT LPNEYKEGKL QAYKLICAMM 1020
TRRQDVLPNS DFLVHFYLVM HLGLTSEDQD VLNTIIKNCS PRFFSLGLPG FSMLVGDFIT 1080
AAARVLSTDM LAAPRSEALT LLGSLVCFPN TYQEIPLLQS VPEVSDVVTG AEDVKHYLIN 1140
ILLKNATEEP NECARCIAIC SLGVWICEEL AQCASHPQVK DAINVIGVTL KFPNKIVAQV 1200
ACDVLQLLVS YWEKLQMFET ALPRKMAEIL VATIAFLLPS AEYSSVETDK KFIVSLLLCL 1260
LDWCMALPVS ALLHPVSTAV IEELHPSRAP LLDYIYRVLH CCVCGSSTYT QQSHYTLTLA 1320
DLSSTDYDPF LPLANVRNSE PVQYHSSADL GNLLTVEEEK KRRSVELIPL TARMVMAHLV 1380
NHLGHYPLSG GPAVLHSLVS ENHDNAHVEG TELSSEVFRS PNLQLFVFND STLISYLQTP 1440
AEGPAGGTSG GSLSDVRVIV RDISGKYSWD GKVLYGPLEG RLAPSGRNPS FQISGWHHHT 1500
CGPQSNLFHG EEGDDVLDKL LENIGHTSPE CLLPSQLNLN EPSPTPSAMN CDQEKEIIEV 1560
ILRQSTQEDE YVQRCHSNSA VKVTSQGQPS PVEPRGPFYF CRLLLDDLGM NSWDRRKNFH 1620
LLKKNSKLLR ELKNLDSRQC RETHKIAVFY IAEGQEDKCS ILANERGSQA YEDFVAGLGW 1680
EVDLSTHCGF MGGLQRNGST GQTAPYYATS TVEVIFHVST RMPSDSDDSL TKKLRHLGND 1740
EVHIVWSEHS RDYRRGIIPT AFGDVSIIIY PMKNHMFFIT ITKKPEVPFF GPLFDGAIVS 1800
GKLLPSLICA TCINASRAVK CLIPLYQSFY EERALYLEAI IQNHREVMTF EDFAAQVFSP 1860
SPSYSLSGTG 1870 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0005096; F:GTPase activator activity; IEA:InterPro.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR016024; ARM-type_fold.
 IPR000331; Rap_GAP_dom.
 IPR027107; Tuberin/Ral-act_asu. 
Pfam
 PF02145; Rap_GAP 
SMART
  
PROSITE
 PS50085; RAPGAP 
PRINTS