CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025395
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Potassium voltage-gated channel subfamily H member 1 
Protein Synonyms/Alias
  
Gene Name
 Kcnh1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
174QLAPSVQKGENVHKHubiquitination[1]
497NSVRDFLKLYQVPKGubiquitination[1]
503LKLYQVPKGLSERVMubiquitination[1]
550HLNRKVFKEHPAFRLubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Ion channel; Ion transport; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 962 AA 
Protein Sequence
MTMAGGRRGL VAPQNTFLEN IVRRSNDTNF VLGNAQIVDW PIVYSNDGFC KLSGYHRAEV 60
MQKSSACSFM YGELTDKDTV EKVRQTFENY EMNSFEILMY KKNRTPVWFF VKIAPIRNEQ 120
DKVVLFLCTF SDITAFKQPI EDDSCKGWGK FARLTRALTS SRGVLQQLAP SVQKGENVHK 180
HSRLAEVLQL GSDILPQYKQ EAPKTPPHII LHYCVFKTTW DWIILILTFY TAILVPYNVS 240
FKTRQNNVAW LVVDSIVDVI FLVDIVLNFH TTFVGPAGEV ISDPKLIRMN YLKTWFVIDL 300
LSCLPYDVIN AFENVDEGIS SLFSSLKVVR LLRLGRVARK LDHYIEYGAA VLVLLVCVFG 360
LAAHWMACIW YSIGDYEIFD EDTKTIRNNS WLYQLALDIG TPYQFNGSGS GKWEGGPSKN 420
SVYISSLYFT MTSLTSVGFG NIAPSTDIEK IFAVAIMMIG SLLYATIFGN VTTIFQQMYA 480
NTNRYHEMLN SVRDFLKLYQ VPKGLSERVM DYIVSTWSMS RGIDTEKVLQ ICPKDMRADI 540
CVHLNRKVFK EHPAFRLASD GCLRALAMEF QTVHCAPGDL IYHAGESVDS LCFVVSGSLE 600
VIQDDEVVAI LGKGDVFGDV FWKEATLAQS CANVRALTYC DLHVIKRDAL QKVLEFYTAF 660
SHSFSRNLIL TYNLRKRIVF RKISDVKREE EERMKRKNEA PLILPPDHPV RRLFQRFRQQ 720
KEARLAAERG GRDLDDLDVE KGNALTDHTS ANHSLVKASV VTVRESPATP VSFQAATTST 780
MSDHAKLHAP GSECLGPKAV SCDPAKRKGW ARFKDACGKG EDWNKVSKAE SMETLPERTK 840
APGEATLKKT DSCDSGITKS DLRLDNVGET RSPQDRSPIL AEVKHSFYPI PEQTLQATVL 900
EVKYELKEDI KALNAKMTSI EKQLSEILRI LMSRGSAQSP QETGEISRPQ SPESDRDIFG 960
AS 962 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
 GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
 GO:0023014; P:signal transduction by phosphorylation; IEA:GOC. 
Interpro
 IPR018490; cNMP-bd-like.
 IPR000595; cNMP-bd_dom.
 IPR005821; Ion_trans_dom.
 IPR003949; K_chnl_volt-dep_EAG.
 IPR003938; K_chnl_volt-dep_EAG/ELK/ERG.
 IPR001610; PAC.
 IPR000014; PAS.
 IPR000700; PAS-assoc_C.
 IPR014710; RmlC-like_jellyroll. 
Pfam
 PF00027; cNMP_binding
 PF00520; Ion_trans 
SMART
 SM00100; cNMP
 SM00086; PAC
 SM00091; PAS 
PROSITE
 PS50042; CNMP_BINDING_3
 PS50113; PAC
 PS50112; PAS 
PRINTS
 PR01463; EAGCHANLFMLY.
 PR01464; EAGCHANNEL.