| Tag | Content |
|---|
| CPLM ID | CPLM-002991 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Peptidase E |
Protein Synonyms/Alias | Alpha-aspartyl dipeptidase; Asp-specific dipeptidase; Dipeptidase E |
Gene Name | pepE |
Gene Synonyms/Alias | b4021; JW3981 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 111 | APITDVVKRGALYIG | acetylation | [1] | | 215 | PNTTYVFKAGEEAVP | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity). |
Sequence Annotation | ACT_SITE 120 120 Charge relay system (By similarity).
ACT_SITE 135 135 Charge relay system (By similarity).
ACT_SITE 157 157 Charge relay system (By similarity). |
Keyword | Complete proteome; Cytoplasm; Dipeptidase; Hydrolase; Protease; Reference proteome; Serine protease. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 229 AA |
Protein Sequence | MELLLLSNST LPGKAWLEHA LPLIAEQLQG RRSAVFIPFA GVTQTWDDYT AKTAAVLAPL 60
GVSVTGIHSV VDPVAAIENA EIVIVGGGNT FQLLKQCRER GLLAPITDVV KRGALYIGWS 120
AGANLACPTI RTTNDMPIVD PQGFDALNLF PLQINPHFTN ALPEGHKGET REQRIRELLV 180
VAPELTIIGL PEGNWITVSK GHATLGGPNT TYVFKAGEEA VPLEAGHRF 229 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |