CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-019699
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADIPOR-like receptor IZH4 
Protein Synonyms/Alias
 Implicated in zinc homeostasis protein 4 
Gene Name
 IZH4 
Gene Synonyms/Alias
 YOL101C 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
20KCETTTEKESNDTRGubiquitination[1]
37SNENAETKETKKGFPubiquitination[1]
41AETKETKKGFPFHDLubiquitination[2]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Sites of ubiquitin attachment in Saccharomyces cerevisiae.
 Starita LM, Lo RS, Eng JK, von Haller PD, Fields S.
 Proteomics. 2012 Jan;12(2):236-40. [PMID: 22106047
Functional Description
 ADIPOR-like receptor involved in zinc metabolism either by altering membrane sterol content or by directly altering cellular zinc levels. 
Sequence Annotation
  
Keyword
 Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 312 AA 
Protein Sequence
MVSLTTIEQS PVKCETTTEK ESNDTRGTDS NENAETKETK KGFPFHDLAK LQKQYKNKSS 60
RNESLVALIY LLGSMLSFCL LIFFTDFYLI PLFPTTTTMT DYIVFNFYLL NVFVFCMVHF 120
IYHFVKNISL QQHLEHWQKF SYLSNINLLI SSQITILYYL FYDYVFFFKI FTLLMNFIGL 180
VAYFFILTDK LISSKRFNKT VFFISVSVVC CSLPLLTAII TFDGLENLKE RIKVNAITWE 240
LVALVAASII YVTRFPESLF RRNKKEEGWN HSEYLFHLLI SGTAFYHFFI LIQSYILMHS 300
SLNQPELINF KS 312 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0016021; C:integral to membrane; ISM:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0046872; F:metal ion binding; ISS:SGD.
 GO:0044255; P:cellular lipid metabolic process; TAS:SGD.
 GO:0006882; P:cellular zinc ion homeostasis; IMP:SGD. 
Interpro
 IPR004254; HlyIII-related. 
Pfam
 PF03006; HlyIII 
SMART
  
PROSITE
  
PRINTS