UniProt Accession

 Q5TF85_HUMAN; Q5TF85 

Genbank Protein ID

 AL078599; AL122017; AL359693; CH471051 

Genbank Nucleotide ID

 EAW48691.1 

Protein Name

 Family with sequence similarity 46, member A, isoform CRA_a 

Protein Synonyms/Alias

 Protein FAM46A 

Gene Name

 FAM46A 

Gene Synonyms/Alias

 hCG_401094 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
298	SGKNVELKFVDSLRR	ubiquitination	[1]
376	IRGGGLLKYCNLLVR	ubiquitination	[2]
393	RPASDEIKTLQRYMC	ubiquitination	[2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 523 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR012937; DUF1693. 

Pfam

 PF07984; DUF1693 

SMART

  

PROSITE

  

PRINTS