CPLM-019649

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-019649

UniProt Accession

OSBL9_HUMAN; Q96SU4; B1AKJ8; B3KPQ4; D3DQ31; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q9H9X2

Genbank Protein ID

AF392445; AY178997; AK022554; AK027535; AK027707; AK056617; AK091703; CR457288; AL772260; AL050343; AL831767; AL772260; AL050343; AL831767; AL831767; AL050343; AL772260; AL831767; AL050343; AL772260; AL050343; AL772260; AL831767; AL050343; AL772260; AL831767; AL050343; CH471059; CH471059; CH471059; CH471059; CH471059; BC025978

Genbank Nucleotide ID

AAL40658.1; AAO20108.1; BAB14096.1; BAB55184.1; BAB55312.1; BAG51766.1; BAC03727.1; CAG33569.1; CAH71118.1; CAH71118.1; CAH71118.1; CAH71119.1; CAH71119.1; CAH71119.1; CAI14843.1; CAI14843.1; CAI14843.1; CAI14844.1; CAI14844.1; CAI14844.1; CAI22219.1; CAI22219.1; CAI22219.1; CAI22220.1; CAI22220.1; CAI22220.1; CAI22221.1; EAX06810.1; EAX06813.1; EAX06816.1; EAX06819.1; EAX06817.1; AAH25978.1

Protein Name

Oxysterol-binding protein-related protein 9

Protein Synonyms/Alias

ORP-9; OSBP-related protein 9

Gene Name

OSBPL9

Gene Synonyms/Alias

ORP9; OSBP4

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
670	YESRSLWKDVTFNLK	ubiquitination	[1]

Reference

[1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]

Functional Description

Sequence Annotation

DOMAIN 2 99 PH.
MOD_RES 2 2 N-acetylalanine.
MOD_RES 326 326 Phosphoserine (By similarity).

Keyword

Acetylation; Alternative splicing; Complete proteome; Lipid transport; Lipid-binding; Phosphoprotein; Polymorphism; Reference proteome; Transport.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

736 AA

Protein Sequence

MASIMEGPLS KWTNVMKGWQ YRWFVLDYNA GLLSYYTSKD KMMRGSRRGC VRLRGAVIGI 60
DDEDDSTFTI TVDQKTFHFQ ARDADEREKW IHALEETILR HTLQLQGLDS GFVPSVQDFD 120
KKLTEADAYL QILIEQLKLF DDKLQNCKED EQRKKIETLK ETTNSMVESI KHCIVLLQIA 180
KDQSNAEKHA DGMISTINPV DAIYQPSPLE PVISTMPSQT VLPPEPVQLC KSEQRPSSLP 240
VGPVLATLGH HQTPTPNSTG SGHSPPSSSL TSPSHVNLSP NTVPEFSYSS SEDEFYDADE 300
FHQSGSSPKR LIDSSGSASV LTHSSSGNSL KRPDTTESLN SSLSNGTSDA DLFDSHDDRD 360
DDAEAGSVEE HKSVIMHLLS QVRLGMDLTK VVLPTFILER RSLLEMYADF FAHPDLFVSI 420
SDQKDPKDRM VQVVKWYLSA FHAGRKGSVA KKPYNPILGE IFQCHWTLPN DTEENTELVS 480
EGPVPWVSKN SVTFVAEQVS HHPPISAFYA ECFNKKIQFN AHIWTKSKFL GMSIGVHNIG 540
QGCVSCLDYD EHYILTFPNG YGRSILTVPW VELGGECNIN CSKTGYSANI IFHTKPFYGG 600
KKHRITAEIF SPNDKKSFCS IEGEWNGVMY AKYATGENTV FVDTKKLPII KKKVRKLEDQ 660
NEYESRSLWK DVTFNLKIRD IDAATEAKHR LEERQRAEAR ERKEKEIQWE TRLFHEDGEC 720
WVYDEPLLKR LGAAKH 736

Gene Ontology

GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006869; P:lipid transport; IEA:UniProtKB-KW.

Interpro

IPR000648; Oxysterol-bd.
IPR018494; Oxysterol-bd_CS.
IPR011993; PH_like_dom.
IPR001849; Pleckstrin_homology.

Pfam

PF01237; Oxysterol_BP
PF00169; PH

SMART

SM00233; PH

PROSITE

PS01013; OSBP
PS50003; PH_DOMAIN

PRINTS