CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002749
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Galactose-1-phosphate uridylyltransferase 
Protein Synonyms/Alias
 Gal-1-P uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase 
Gene Name
 galT 
Gene Synonyms/Alias
 galB; b0758; JW0741 
Created Date
 July 27, 2013 
Organism
 Escherichia coli (strain K12) 
NCBI Taxa ID
 83333 
Lysine Modification
Position
Peptide
Type
References
30LVSPHRAKRPWQGAQacetylation[1]
117CFSPDHSKTLPELSVacetylation[1]
132AALTEIVKTWQEQTAacetylation[1]
187EREDRLQKEYFAEQKacetylation[1]
194KEYFAEQKSPMLVDYacetylation[2]
Reference
 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 
Functional Description
  
Sequence Annotation
 ACT_SITE 166 166 Tele-UMP-histidine intermediate.
 METAL 52 52 Zinc.
 METAL 55 55 Zinc.
 METAL 115 115 Zinc.
 METAL 164 164 Zinc.
 METAL 182 182 Iron.
 METAL 281 281 Iron.
 METAL 296 296 Iron.
 METAL 298 298 Iron.  
Keyword
 3D-structure; Carbohydrate metabolism; Complete proteome; Galactose metabolism; Iron; Metal-binding; Nucleotidyltransferase; Reference proteome; Transferase; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 348 AA 
Protein Sequence
MTQFNPVDHP HRRYNPLTGQ WILVSPHRAK RPWQGAQETP AKQVLPAHDP DCFLCAGNVR 60
VTGDKNPDYT GTYVFTNDFA ALMSDTPDAP ESHDPLMRCQ SARGTSRVIC FSPDHSKTLP 120
ELSVAALTEI VKTWQEQTAE LGKTYPWVQV FENKGAAMGC SNPHPHGQIW ANSFLPNEAE 180
REDRLQKEYF AEQKSPMLVD YVQRELADGS RTVVETEHWL AVVPYWAAWP FETLLLPKAH 240
VLRITDLTDA QRSDLALALK KLTSRYDNLF QCSFPYSMGW HGAPFNGEEN QHWQLHAHFY 300
PPLLRSATVR KFMVGYEMLA ETQRDLTAEQ AAERLRAVSD IHFRESGV 348 
Gene Ontology
 GO:0008198; F:ferrous iron binding; IDA:EcoCyc.
 GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IDA:EcoCyc.
 GO:0033499; P:galactose catabolic process via UDP-galactose; IMP:EcoCyc. 
Interpro
 IPR001937; GalP_UDPtransf1.
 IPR019779; GalP_UDPtransf1_His-AS.
 IPR005850; GalP_Utransf_C.
 IPR005849; GalP_Utransf_N.
 IPR011146; HIT-like. 
Pfam
 PF02744; GalP_UDP_tr_C
 PF01087; GalP_UDP_transf 
SMART
  
PROSITE
 PS00117; GAL_P_UDP_TRANSF_I 
PRINTS