CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041164
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 DNA mismatch repair protein Msh2 
Protein Synonyms/Alias
  
Gene Name
 Msh2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
109KAGNKASKENEWYLAacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 210 AA 
Protein Sequence
XKETLQLEGA AEAGFVRFFE GMPEKPSTTV RLFDRGDFYT AHGEDALLAA REVFKTQGVI 60
KYMGPAGSKT LQSVVLSKMN FESFVKDLLL VRQYRVEVYK NKAGNKASKE NEWYLAFKVI 120
QRGGILITER KRADFSTKDI YQDLNRLLKG KKGEQINSAA LPEMENQVAV SSLSAVIKFL 180
ELLSDDSNFG QFELATFDFS QYMKLDMAAV 210 
Gene Ontology
 GO:0032301; C:MutSalpha complex; IDA:MGI.
 GO:0032302; C:MutSbeta complex; IBA:RefGenome.
 GO:0000228; C:nuclear chromosome; IBA:RefGenome.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0019237; F:centromeric DNA binding; IDA:MGI.
 GO:0003684; F:damaged DNA binding; IMP:MGI.
 GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.
 GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.
 GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.
 GO:0032137; F:guanine/thymine mispair binding; ISO:MGI.
 GO:0000404; F:loop DNA binding; IBA:RefGenome.
 GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.
 GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
 GO:0030183; P:B cell differentiation; IMP:MGI.
 GO:0007050; P:cell cycle arrest; IMP:MGI.
 GO:0008340; P:determination of adult lifespan; IMP:MGI.
 GO:0006302; P:double-strand break repair; IMP:MGI.
 GO:0007281; P:germ cell development; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IGI:MGI.
 GO:0031573; P:intra-S DNA damage checkpoint; IGI:MGI.
 GO:0042771; P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator; IGI:MGI.
 GO:0045190; P:isotype switching; IMP:MGI.
 GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.
 GO:0008584; P:male gonad development; IMP:MGI.
 GO:0006311; P:meiotic gene conversion; IBA:RefGenome.
 GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.
 GO:0043524; P:negative regulation of neuron apoptotic process; IMP:MGI.
 GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.
 GO:0006119; P:oxidative phosphorylation; IMP:MGI.
 GO:0006301; P:postreplication repair; IMP:MGI.
 GO:0010224; P:response to UV-B; IMP:MGI.
 GO:0010165; P:response to X-ray; IMP:MGI.
 GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI. 
Interpro
 IPR007695; DNA_mismatch_repair_MutS-lik_N.
 IPR007860; DNA_mmatch_repair_MutS_con_dom. 
Pfam
 PF01624; MutS_I
 PF05188; MutS_II 
SMART
  
PROSITE
  
PRINTS