CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039377
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Dag1 
Protein Synonyms/Alias
  
Gene Name
 Dag1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
533DTTTDKLKLTLKLREacetylation[1]
537DKLKLTLKLREQQLVacetylation[1]
609APARFKAKLAGDPAPacetylation[1]
623PVVNDIHKKIALVKKacetylation[1]
629HKKIALVKKLAFAFGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 893 AA 
Protein Sequence
MSVDNWLLHP LWGQTFLLLL SVAVAQAHWP SEPSEAVRDW KNQLEASMHS VLSDFQEAVP 60
TVVGIPDGTA VVGRSFRVSI PTDLIASSGE IIKVSAAGKE ALPSWLHWDP HSHILEGLPL 120
DTDKGVHYIS VSAARLGANG SHVPQTASVF SIEVYPEDHS EPQSVRAASS DPGEVVSSAC 180
AADEPVTVLT VILDADLTKM TPKQRIDLLN RMQSFSEVEL NNMKLVPVVN NRLFDMSAFM 240
AGPGNAKKVV ENGALLSWKL GCSLNQNSVP DIRGVETPAR EGTMSAHLGY PVVGWHIANK 300
KPTLPKRIRR QIHATPTPVT AIGPPTTAIQ EPPSRIVPTP TSPAIAPPTE TMAPPVRDPV 360
PGKPTVTIRT RGAIIQTPTL GPIPPTRVSE AGTTVPGQIR PTLTIPGYVE PTAVVTPPTT 420
TTKKPRVSTP KPATPSTDSS TTTTRRPTKK PRTPRPVPRV TTKAPITRLE TASPPTRIRT 480
TTSAVPRGGE ANQRPELKNH IDRVDAWVGT YFEVKIPSDT FYDNEDTTTD KLKLTLKLRE 540
QQLVGEKSWV QFNSNSQLMY GLPDSSHVGK HEYFMHATDK GGLSAVDAFE IHVHKRPQGD 600
KAPARFKAKL AGDPAPVVND IHKKIALVKK LAFAFGDRNC SSITLQNITR GSIVVEWTNN 660
TLPLEPCPKE QIVGLSRRIA DENGKPRPAF SNALEPDFKA LSVAVAGSGS CRHLQFIPVA 720
PPSPGTSAAP ATEVPDRDPE KSSEDDVYLH TVIPAVVVAA ILLIAGIIAM ICYRKKRKGK 780
LTLEDQATFI KKGVPIIFAD ELDDSKPPPS SSMPLILQEE KAPLPPPEYP NQSVPETTPL 840
NQDTVGEYTP LRDEDPNAPP YQPPPPFTAP MEGKGSRPKN MTPYRSPPPY VPP 893 
Gene Ontology
 GO:0005604; C:basement membrane; IEA:Compara.
 GO:0016323; C:basolateral plasma membrane; IDA:RGD.
 GO:0009279; C:cell outer membrane; IEA:Compara.
 GO:0005913; C:cell-cell adherens junction; IDA:RGD.
 GO:0070938; C:contractile ring; IEA:Compara.
 GO:0043034; C:costamere; IDA:RGD.
 GO:0016011; C:dystroglycan complex; IEA:Compara.
 GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:RGD.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0030175; C:filopodium; IEA:Compara.
 GO:0005925; C:focal adhesion; IDA:RGD.
 GO:0016021; C:integral to membrane; IEA:Compara.
 GO:0030027; C:lamellipodium; IEA:Compara.
 GO:0045121; C:membrane raft; IEA:Compara.
 GO:0033268; C:node of Ranvier; IEA:Compara.
 GO:0005654; C:nucleoplasm; IEA:Compara.
 GO:0042383; C:sarcolemma; IDA:RGD.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0008307; F:structural constituent of muscle; IEA:Compara.
 GO:0060445; P:branching involved in salivary gland morphogenesis; IEA:Compara.
 GO:0016340; P:calcium-dependent cell-matrix adhesion; IMP:RGD.
 GO:0007016; P:cytoskeletal anchoring at plasma membrane; IEA:InterPro.
 GO:0060441; P:epithelial tube branching involved in lung morphogenesis; IEA:Compara.
 GO:0006509; P:membrane protein ectodomain proteolysis; IEA:Compara.
 GO:0034453; P:microtubule anchoring; IEA:Compara.
 GO:0002011; P:morphogenesis of an epithelial sheet; IEA:Compara.
 GO:0022011; P:myelination in peripheral nervous system; IEA:Compara.
 GO:0030336; P:negative regulation of cell migration; IEA:Compara.
 GO:0043409; P:negative regulation of MAPK cascade; IEA:Compara.
 GO:0051898; P:negative regulation of protein kinase B signaling cascade; IEA:Compara.
 GO:0021682; P:nerve maturation; IEA:Compara.
 GO:0006607; P:NLS-bearing substrate import into nucleus; IEA:Compara.
 GO:0043434; P:response to peptide hormone stimulus; IEP:RGD.
 GO:0019048; P:virus-host interaction; IEA:Compara. 
Interpro
 IPR027468; Alpha-dystroglycan_domain_2.
 IPR006644; Cadg.
 IPR015919; Cadherin-like.
 IPR008465; DAG1.
 IPR013783; Ig-like_fold. 
Pfam
 PF05454; DAG1 
SMART
 SM00736; CADG 
PROSITE
  
PRINTS