| Tag | Content |
|---|
| CPLM ID | CPLM-021901 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 2-hydroxyacyl-CoA lyase |
Protein Synonyms/Alias | 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Oxalyl-CoA decarboxylase |
Gene Name | HACL |
Gene Synonyms/Alias | HPCL; OCD; At5g17380; T10B6.40 |
Created Date | July 27, 2013 |
Organism | Arabidopsis thaliana (Mouse-ear cress) |
NCBI Taxa ID | 3702 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 4 | ****MADKSETTPPS | acetylation | [1] |
|
Reference | [1] Proteins of diverse function and subcellular location are lysine acetylated in Arabidopsis. Finkemeier I, Laxa M, Miguet L, Howden AJ, Sweetlove LJ. Plant Physiol. 2011 Apr;155(4):1779-90. [ PMID: 21311031] |
Functional Description | Catalyzes a carbon-carbon cleavage reaction; cleaves a 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde (By similarity). |
Sequence Annotation | REGION 407 488 Thiamine pyrophosphate binding (By
METAL 457 457 Magnesium (By similarity).
METAL 484 484 Magnesium (By similarity).
BINDING 58 58 Thiamine pyrophosphate (By similarity). |
Keyword | Complete proteome; Decarboxylase; Lyase; Magnesium; Metal-binding; Reference proteome; Thiamine pyrophosphate. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 572 AA |
Protein Sequence | MADKSETTPP SIDGNVLVAK SLSHLGVTHM FGVVGIPVTS LASRAMALGI RFIAFHNEQS 60
AGYAASAYGY LTGKPGILLT VSGPGCVHGL AGLSNAWVNT WPMVMISGSC DQRDVGRGDF 120
QELDQIEAVK AFSKLSEKAK DVREIPDCVS RVLDRAVSGR PGGCYLDIPT DVLRQKISES 180
EADKLVDEVE RSRKEEPIRG SLRSEIESAV SLLRKAERPL IVFGKGAAYS RAEDELKKLV 240
EITGIPFLPT PMGKGLLPDT HEFSATAARS LAIGKCDVAL VVGARLNWLL HFGESPKWDK 300
DVKFILVDVS EEEIELRKPH LGIVGDAKTV IGLLNREIKD DPFCLGKSNS WVESISKKAK 360
ENGEKMEIQL AKDVVPFNFL TPMRIIRDAI LAVEGPSPVV VSEGANTMDV GRSVLVQKEP 420
RTRLDAGTWG TMGVGLGYCI AAAVASPDRL VVAVEGDSGF GFSAMEVETL VRYNLAVVII 480
VFNNGGVYGG DRRGPEEISG PHKEDPAPTS FVPNAGYHKL IEAFGGKGYI VETPDELKSA 540
LAESFAARKP AVVNVIIDPF AGAESGRLQH KN 572 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |