UniProt Accession

 TBCA_YEAST; P48606; D6W2W5 

Genbank Protein ID

 U30184; Z75173; AY692767; BK006948 

Genbank Nucleotide ID

 AAB08525.1; CAA99488.1; AAT92786.1; DAA11031.1 

Protein Name

 Tubulin-specific chaperone A 

Protein Synonyms/Alias

 Tubulin-folding cofactor A; CFA 

Gene Name

 RBL2 

Gene Synonyms/Alias

 YOR265W 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
18	KALKRLTKEEGYYQQ	acetylation	[1]
18	KALKRLTKEEGYYQQ	ubiquitination	[2]
41	VAKLKEDKSVDPYDL	acetylation	[1]
68	LLPTLYEKIREFKED	acetylation	[1]

Reference

 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Tubulin-folding protein; involved in the early step of the tubulin folding pathway. 

Sequence Annotation

 MOD_RES 94 94 Phosphoserine.  

Keyword

 3D-structure; Chaperone; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 106 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0048487; F:beta-tubulin binding; IMP:SGD.
 GO:0007021; P:tubulin complex assembly; IMP:SGD. 

Interpro

 IPR004226; CofA_tubulin-bd. 

Pfam

 PF02970; TBCA 

SMART

  

PROSITE

  

PRINTS