CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029490
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 GRB2-related adapter protein 
Protein Synonyms/Alias
  
Gene Name
 GRAP 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
9EDDQNWYKAELRGVEubiquitination[1]
21GVEGFIPKNYIRVKPubiquitination[1]
27PKNYIRVKPHPWYSGubiquitination[1]
47LAEEILMKRNHLGAFubiquitination[1]
80GDQVQHFKVLREASGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; SH3 domain. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 188 AA 
Protein Sequence
MEDDQNWYKA ELRGVEGFIP KNYIRVKPHP WYSGRISRQL AEEILMKRNH LGAFLIRESE 60
SSPGEFSVSV NYGDQVQHFK VLREASGKYF LWEEKFNSLN ELVDFYRTTT IAKKRQIFLR 120
DEEPLLKSPG ACFAQAQFDF SAQDPSQLSF RRGDIIEVLE RPDPHWWRGR SCGRVGFFPR 180
SYVQPVHL 188 
Gene Ontology
  
Interpro
 IPR000108; p67phox.
 IPR000980; SH2.
 IPR011511; SH3_2.
 IPR001452; SH3_domain. 
Pfam
 PF00017; SH2
 PF07653; SH3_2 
SMART
 SM00252; SH2
 SM00326; SH3 
PROSITE
 PS50001; SH2
 PS50002; SH3 
PRINTS
 PR00499; P67PHOX.
 PR00401; SH2DOMAIN.
 PR00452; SH3DOMAIN.