| Tag | Content |
|---|
| CPLM ID | CPLM-013036 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Extended synaptotagmin-2 |
Protein Synonyms/Alias | E-Syt2 |
Gene Name | Esyt2 |
Gene Synonyms/Alias | D12Ertd551e; Fam62b |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 329 | QGKDTYLKGLVKGKS | ubiquitination | [1] | | 529 | QDLEVEVKDEQHQCS | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May play a role as calcium-regulated intrinsic membrane protein (By similarity). |
Sequence Annotation | DOMAIN 296 397 C2 1.
DOMAIN 447 541 C2 2.
DOMAIN 712 816 C2 3.
MOD_RES 615 615 Phosphoserine (By similarity).
MOD_RES 662 662 Phosphoserine.
MOD_RES 663 663 Phosphoserine (By similarity).
MOD_RES 667 667 Phosphoserine (By similarity).
MOD_RES 679 679 Phosphoserine (By similarity).
MOD_RES 682 682 Phosphoserine.
MOD_RES 685 685 Phosphoserine. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 845 AA |
Protein Sequence | MSSAGGEGPE AGPGRAGGRS EPEAPGSALS VDLPGLLGQL ARSFALLLPV YALGYLGLSF 60
SWVLLALGLL AWCRRSRGLK ASRLCRALAL LEDEEQAVRL GVRACDLPAW VHFPDTERAE 120
WLNKTVKHMW PFICQFIEKL FRETIEPAVR GANAHLSTFS FTKVDVGQQP LRVNGVKVYT 180
ENVDKRQIIL DLQISFVGNC EIDLEIKRYF CRAGVKSIQI HGTMRVILEP LIGDMPLVGA 240
LSIFFLRKPL LEINWTGLTN LLDIPGLNGL SDTIILDIIS NYLVLPNRIT VPLVSEVQIA 300
QLRFPIPKGV LRIHFIEAQD LQGKDTYLKG LVKGKSDPYG IIRVGNQIFQ SKVIKENLSP 360
KWNEVYEALV YEHPGQELEI ELFDEDPDKD DFLGSLMIDL IEVEKERLLD EWFTLDEVPK 420
GKLHLKLEWL TLMPDAANLD KVLADIRADK DQASDGLSSA LLILYLDSAR NLPSGKKINS 480
NPNPLVQMSV GHKAQESKIR YKTSEPVWEE NFTFFIHNPR RQDLEVEVKD EQHQCSLGSL 540
RIPLSQLLTS DNMTINQRFQ LSNSGPNSTL KMKIALRVLH LEKQERPPDY QHSAQVKRPS 600
VSKEGRKMPI KSQMSASPGT GGANTAPSTP VMGVDDKPAM EEKPQPPEAS PLGHRDLGRS 660
SSSLLASPSH IAAKEPTPSI ASDISLPIAT QELRQRLRQL ENGTTLGQSP LGQIQLTIRH 720
SSQRNKLIVV VHSCRNLIAF SEDGSDPYVR MYLLPDKRRS GRRKTHVSKK TLNPVFDQSF 780
DFSVSLPEVQ RRTLDVAVKN SGGFLSKDKG LLGKVLVVLA SEELAKGWTQ WYDLTEDGTR 840
PQVIT 845 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |