CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031972
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Synaptotagmin-5 
Protein Synonyms/Alias
 cDNA FLJ50152, highly similar to Synaptotagmin-5 
Gene Name
 SYT5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
295KKKTTIKKNTLNPYYubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 382 AA 
Protein Sequence
MTRGGCPVSA RLFAQRPHGS WSSLLCVGLK GRLGWEWGTR VLECLCRKDS RTPPPCSRSP 60
QPRGLHRPTR LPTPVASATA QVQPEVEELE PAPSGPGQQV ADKHELGRLQ YSLDYDFQSG 120
QLLVGILQAM GLAALDLGGS SDPYVRVYLL PDKRRRYETK VHRQTLNPHF GETFAFKVPY 180
VELGGRVLVM AVYDFDRFSR NDAIGEVRVP MSSVDLGRPV QAWRELQAAP REEEKLGDIC 240
FSLRYVPTAG KLTVIVLEAK NLKKMDVGGL SDPYVKVHLL QGGKKVRKKK TTIKKNTLNP 300
YYNEAFSFEV PCDQVQKVQV ELTVLDYDKL GKNEAIGRVA VGAAAGGAGL RHWADMLANP 360
RRPIAQWHSL RPPDRVRLLP AP 382 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0008021; C:synaptic vesicle; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro. 
Interpro
 IPR000008; C2_Ca-dep.
 IPR008973; C2_Ca/lipid-bd_dom_CaLB.
 IPR020477; C2_dom.
 IPR018029; C2_membr_targeting.
 IPR001565; Synaptotagmin. 
Pfam
 PF00168; C2 
SMART
 SM00239; C2 
PROSITE
 PS50004; C2 
PRINTS
 PR00360; C2DOMAIN.
 PR00399; SYNAPTOTAGMN.