UniProt Accession

 H0Y6H0_HUMAN; H0Y6H0 

Genbank Protein ID

 AL031774; AL589723 

Genbank Nucleotide ID

  

Protein Name

 Lysine-specific histone demethylase 1B 

Protein Synonyms/Alias

  

Gene Name

 KDM1B 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
67	TGNASPGKLEHSKAA	ubiquitination	[1]
195	ADQYLLPKDYHNKSV	ubiquitination	[2]
298	ITDPTIDKRMDFHFN	ubiquitination	[1, 3]
335	EKIEEIYKAFIKESG	ubiquitination	[2, 4]
467	PLSEKKMKAINSLGA	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 640 AA 

Protein Sequence

Gene Ontology

 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0016491; F:oxidoreductase activity; IEA:InterPro. 

Interpro

 IPR002937; Amino_oxidase.
 IPR009057; Homeodomain-like.
 IPR007526; SWIRM.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF01593; Amino_oxidase 

SMART

  

PROSITE

 PS50934; SWIRM 

PRINTS