CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044935
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Thimet oligopeptidase 
Protein Synonyms/Alias
  
Gene Name
 THOP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
4****XEGKYGHAACFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Metal-binding; Metalloprotease; Protease; Reference proteome; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 260 AA 
Protein Sequence
XEGKYGHAAC FGLQPGCLRQ DGSRQIAIAA MVANFTKPTA DAPSLLQHDE VETYFHEFGH 60
VMHQLCSQAE FAMFSGTHVE RDFVEAPSQM LENWVWEQEP LLRMSRHYRT GSAVPRELLE 120
KLIESRQANT GLFNLRQIVL AKVDQALHTQ TDADPAEEYA RLCQEILGVP ATPGGYDAQY 180
YGYLWSEVYS MDMFHTRFKQ EGVLNSKVGM DYRSCILRPG GSEDASAMLR RFLGRDPKQD 240
AFLLSKGLQV GGCEPEPQVC 260 
Gene Ontology
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
 GO:0006508; P:proteolysis; IEA:UniProtKB-KW. 
Interpro
 IPR024079; MetalloPept_cat_dom.
 IPR024077; Neurolysin/TOP_dom2.
 IPR001567; Pept_M3A_M3B. 
Pfam
 PF01432; Peptidase_M3 
SMART
  
PROSITE
  
PRINTS