| Tag | Content |
|---|
| CPLM ID | CPLM-016597 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | NACHT, LRR and PYD domains-containing protein 4A |
Protein Synonyms/Alias | NALP-ita |
Gene Name | Nlrp4a |
Gene Synonyms/Alias | Nalp4a |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 750 | LISNKTLKHLNLASN | acetylation | [1] |
|
Reference | [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3. Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C. PLoS One. 2012;7(12):e50545. [ PMID: 23236377] |
Functional Description | May be involved in inflammation. |
Sequence Annotation | DOMAIN 1 93 DAPIN.
DOMAIN 148 471 NACHT.
REPEAT 594 618 LRR 1.
REPEAT 634 658 LRR 2.
REPEAT 689 712 LRR 3.
REPEAT 746 773 LRR 4.
REPEAT 777 801 LRR 5.
REPEAT 802 825 LRR 6.
REPEAT 827 847 LRR 7.
REPEAT 859 882 LRR 8.
REPEAT 888 911 LRR 9.
REPEAT 916 943 LRR 10.
NP_BIND 154 161 ATP (Potential). |
Keyword | ATP-binding; Complete proteome; Leucine-rich repeat; Nucleotide-binding; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 982 AA |
Protein Sequence | MASFFSDFGL MWYLEELNKK EFVKFKEFLK QEVLQLGLKQ VSWTEVKKAS RQDLASLLLK 60
HYEEKPAWDM TFRFFQKINR KDLIERAKRE IDGCPKLYRA HMKTKMTHDS SRAFTISIQN 120
FLKEKFTEDD YDCFENLFQS KGTESKPQVV FLSGGAGVGK TLMLKRLMLA WIESPVFLHK 180
FSYIFYFCCR EVKQLKTASL AELISREWPG PSAPIEEILS KPEKLLFIID SLEGMECDLF 240
KWESELCDNC TEKQPVNVLL SSLLRRKMLP ESSLLISATP ESFEKMENRI EYTHVKIIKG 300
LKERNIKMSF HRLFQDRNRA HEAFSLVREN EQLFTVCQVP VLCWMVATCL KEEIEKGRDP 360
VSICRCTTSL YTTHIFNLFI PQNAHSPSKK SQDQLQGLCS LAAEGMWTDT FVFGEEALRR 420
NGIMDSDIPI LLDIGMLINI RESEKSYIFL HPSVQEVCAA IFYLLKSHVD HPSQEVKSIE 480
KLMFAFLKKV KVQWIFFGSF IFGLLHESEQ KKLEAFFGHQ LSQEIKRQLY QCLETISGNE 540
ELQEQIDGMK LFYCLFEMDD DTFLVEAMNC MEQINFVAKD YSDVIVAAHC LKHCFTLKKL 600
SFSTQNVLSG AQEHSYMERL LTAWNHICSV FIISKDIQEL RMKDTNLSES AFSVLYNNLK 660
YHNYTLNVLV ANNVFFVCEK YLFFELIQNC NLQHLNLSLT ILSHSDVKLL CDVLSQAECN 720
IEELVVAACS ISSDDCKVFA SVLISNKTLK HLNLASNTLD KGIASLCKSL CHPDCILEHL 780
VLANCSLNEK CWDYLSEVLR RNKTLSHLDI SSNDLKDEGL KVLCRALTLP DSVLKSLSLR 840
HCLITISGCQ DLAEVLRNNQ NLVSLQVSNN KLEDTGVKLL CDAIKHPNCH LEDLGLEACE 900
LTGACCEDLA STFTQCKTLW AMNLLKNALD YNGLVVLCEA LKQQTCATYV LGLQITDFDT 960
ETQAFLVAEQ EKNPCLRILS SL 982 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |