CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032858
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Pyridoxine/pyridoxal 5-phosphate biosynthesis enzyme 
Protein Synonyms/Alias
  
Gene Name
 PFF1025c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
189SEVYHFAKKINAPIDacetylation[1]
296NKNEEHTKFLTPQ**acetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 301 AA 
Protein Sequence
MENHKDDAVL LKHGWCEMLK GGVIMDVKSV EQAKIAEEAG AIGVMVLENI PSELRNKEGV 60
ARSVDPSKVE EIKKCVSINV LAKVRIGHFV EAQILEELKI DMIDESEVLT IADEMHHIDK 120
HKFKTPFVCG CTNLGEALRR ISEGASMIRT KGEAGTGNII EAIKHIRTVN NEIKYLCSLS 180
DSEVYHFAKK INAPIDLVLL TKKLKRLPVV NFAAGGVATP ADAAMCMQLG MDGVFVGSGI 240
FESENPRKMA ASIVSAVSNF NNPKILLDVS MNLGKAMCGS TRVSDKWKNK NEEHTKFLTP 300
Q 301 
Gene Ontology
 GO:0003824; F:catalytic activity; ISS:GeneDB_Pfalciparum.
 GO:0042823; P:pyridoxal phosphate biosynthetic process; IEA:InterPro.
 GO:0008615; P:pyridoxine biosynthetic process; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR011060; RibuloseP-bd_barrel.
 IPR001852; Snz1p/Sor1. 
Pfam
 PF01680; SOR_SNZ 
SMART
  
PROSITE
 PS01235; PDXS_SNZ_1
 PS51129; PDXS_SNZ_2 
PRINTS