CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026276
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Acidic leucine-rich nuclear phosphoprotein 32 family member B 
Protein Synonyms/Alias
  
Gene Name
 ANP32B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
18HLNLSGNKLKDISTLacetylation[1]
18HLNLSGNKLKDISTLubiquitination[1, 2]
20NLSGNKLKDISTLEPacetylation[1, 3]
20NLSGNKLKDISTLEPubiquitination[1, 2, 4]
29ISTLEPLKKLECLKSacetylation[1]
29ISTLEPLKKLECLKSubiquitination[4]
30STLEPLKKLECLKSLubiquitination[4]
35LKKLECLKSLDLFNCubiquitination[4]
Reference
 [1] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Leucine-rich repeat; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 156 AA 
Protein Sequence
MLAEKLPNLT HLNLSGNKLK DISTLEPLKK LECLKSLDLF NCEVTNLNDY RESVFKLLPQ 60
LTYLDGYDRE DQEAPDSDAE VDGVDEEEED EEGEDEEDED DEDGEEEEFD EEDDEDEDVE 120
GDEDDDEVSE EEEEFGLDEE DEDEDEDEEE EEGGKG 156 
Gene Ontology
  
Interpro
 IPR001611; Leu-rich_rpt.
 IPR025875; Leu-rich_rpt_4.
 IPR003603; U2A'_phosphoprotein32A_C. 
Pfam
 PF12799; LRR_4 
SMART
 SM00446; LRRcap 
PROSITE
 PS51450; LRR 
PRINTS