CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006236
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Exocyst complex component SEC8 
Protein Synonyms/Alias
  
Gene Name
 SEC8 
Gene Synonyms/Alias
 YPR055W; YP9499.11 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
134CLKEANEKITTDKGSubiquitination[1]
139NEKITTDKGSLQELNubiquitination[1, 2]
Reference
 [1] Identification, analysis, and prediction of protein ubiquitination sites.
 Radivojac P, Vacic V, Haynes C, Cocklin RR, Mohan A, Heyen JW, Goebl MG, Iakoucheva LM.
 Proteins. 2010 Feb 1;78(2):365-80. [PMID: 19722269]
 [2] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 
Functional Description
 Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. 
Sequence Annotation
 MOD_RES 16 16 Phosphoserine.
 MOD_RES 19 19 Phosphoserine.  
Keyword
 Cell membrane; Coiled coil; Complete proteome; Cytoplasm; Exocytosis; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1065 AA 
Protein Sequence
MDYLKPAQKG RRRGLSINSL SETQQSAMNS SLDHLQNDLN RINLQWNRIL SDNTNPLELA 60
LAFLDDTSVG LGHRYEEFNQ LKSQIGSHLQ DVVNEHSQVF NTNVASYGKA VSSIMQAQEQ 120
TLNLKNCLKE ANEKITTDKG SLQELNDNNL KYTKMIDVLV NIEELLQIPE KIEENIRKEN 180
FHQVQILLER GFILMNNKSL KTVEILKPIN QQLELQEHLL FNNLIEEIHD IMYSKSNKTN 240
FTRVTNNDIF KIISISHNGF TSLENYLYNI VNIDIMEHSK TINKNLEQFI HDQSLNKGNI 300
MLQENAATQA PLAPSRNQEN EGFNRIGFLL KTINNINKLP VAFNIITERA KEEIHNIIVK 360
STESIRSKHP SLLKMATSLK NDNHFGLPVQ DILSIILREC FWEIFLKLLY AIQCHRAIFE 420
MSNILQPTSS AKPAFKFNKI WGKLLDEIEL LLVRYINDPE LISSNNGSIK PINGATNNAP 480
TLPKRKNPKI FSLEYNIEDN SSVKDQAFEL KALLKDIFPG FSVSSNMDLD SIYVKDESFE 540
QDEPLVPPSV FNMKVILDPF LLFTQSTSTI VPSVLTQNTI SSLTFFDDYM NKSFLPKIQM 600
TMDYLFTVEV ESNNPYALEL SDENHNIFKT ALDFQRLFYN LLNVFNTANT FREKISYCIL 660
DLLNHFYNYY LGLFNSLIGT SDRHLTRKII TAWLQNGILM DQEQKILNGD ETLFHEESIE 720
LFKEIPHFYQ AGKGLSKSDL FNNLTLDTIL QFSASVLWIL NWLPGLKKAI NIDEVSQEPM 780
LDADRLRSSW TFSESMDLNY SNPSSSPNSL GNLKILLDDK ASKKFDETID GFKTLKFKLI 840
TILRFNIRAL CIYDIGSFFQ NTKIWNMDVG SIELDQNIAS LISELRRTES KLKQQLPEKE 900
KNSIFIGLDI VNNYALIKGA KSIKVLNHNG IKKMLRNVNV LQHAYRNLSS EPSKINMNVT 960
MNFYSLCGSS EAELFEYIKD NELPHCSVED LKTILRLQFS EEMHRQLKRQ STSSTKGSIK 1020
PSNKRYTEAL EKLSNLEKEQ SKEGARTKIG KLKSKLNAVH TANEK 1065 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0005934; C:cellular bud tip; IDA:SGD.
 GO:0000145; C:exocyst; IDA:SGD.
 GO:0000131; C:incipient cellular bud site; IDA:SGD.
 GO:0043332; C:mating projection tip; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.
 GO:0048313; P:Golgi inheritance; IMP:SGD.
 GO:0006893; P:Golgi to plasma membrane transport; IMP:SGD.
 GO:0015031; P:protein transport; IEA:UniProtKB-KW.
 GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro.
 GO:0090522; P:vesicle tethering involved in exocytosis; IC:SGD. 
Interpro
 IPR007191; Sec8_exocyst. 
Pfam
 PF04048; Sec8_exocyst 
SMART
  
PROSITE
  
PRINTS