UniProt Accession

 D6R927_HUMAN; D6R927 

Genbank Protein ID

 AC093637; AC097109; AC097714; AC111003 

Genbank Nucleotide ID

  

Protein Name

 Recombining-binding protein suppressor of hairless 

Protein Synonyms/Alias

  

Gene Name

 RBPJ 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
121	LYISDSDKRKHFMLS	ubiquitination	[1]
161	SKKKQSLKNADLCIA	ubiquitination	[2]
277	HKCAFYLKDTERMYL	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 382 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0000978; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding; IEA:InterPro.
 GO:0000982; F:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity; IEA:InterPro. 

Interpro

 IPR015350; Beta-trefoil_DNA-bd_dom.
 IPR014756; Ig_E-set.
 IPR015351; LAG1_DNA-bd.
 IPR008967; p53-like_TF_DNA-bd. 

Pfam

 PF09270; BTD
 PF09271; LAG1-DNAbind 

SMART

  

PROSITE

  

PRINTS