CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006375
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein SKT5 
Protein Synonyms/Alias
  
Gene Name
 SKT5 
Gene Synonyms/Alias
 CAL2; CHS4; CSD4; YBL061C; YBL0506; YBL0519 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
44GQDFSDNKENRENRDubiquitination[1]
139NSSTSLTKEQIKKRTubiquitination[1]
634RKSSSSAKGMSREVAacetylation[2]
664GSSNMIRKDFPAVKTubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] mChIP-KAT-MS, a method to map protein interactions and acetylation sites for lysine acetyltransferases.
 Mitchell L, Huard S, Cotrut M, Pourhanifeh-Lemeri R, Steunou AL, Hamza A, Lambert JP, Zhou H, Ning Z, Basu A, Côté J, Figeys DA, Baetz K.
 Proc Natl Acad Sci U S A. 2013 Apr 23;110(17):E1641-50. [PMID: 23572591] 
Functional Description
 Possible role in protoplast regeneration and killer toxin of K.lactis (PGKL) resistance. 
Sequence Annotation
 REPEAT 271 306 Sel1-like 1.
 REPEAT 307 342 Sel1-like 2.
 REPEAT 343 382 Sel1-like 3.
 REPEAT 386 423 Sel1-like 4.
 REPEAT 424 460 Sel1-like 5.
 REPEAT 461 498 Sel1-like 6.
 REPEAT 499 534 Sel1-like 7.
 MOD_RES 148 148 Phosphoserine.
 MOD_RES 561 561 Phosphoserine.
 MOD_RES 563 563 Phosphoserine.
 MOD_RES 564 564 Phosphothreonine.
 MOD_RES 693 693 Cysteine methyl ester (By similarity).
 LIPID 693 693 S-farnesyl cysteine (By similarity).  
Keyword
 Cell membrane; Complete proteome; Lipoprotein; Membrane; Methylation; Phosphoprotein; Prenylation; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 696 AA 
Protein Sequence
MASSPQVHPY KKHLMQSQHI NFDNRGLQFQ NSSLKVGQDF SDNKENRENR DNEDFSTADL 60
PKRSANQPLI NEHLRAASVP LLSNDIGNSQ EEDFVPVPPP QLHLNNSNNT SLSSLGSTPT 120
NSPSPGALRQ TNSSTSLTKE QIKKRTRSVD LSHMYLLNGS SDTQLTATNE SVADLSHQMI 180
SRYLGGKNNT SLVPRLKTIE MYRQNVKKSK DPEVLFQYAQ YMLQTALTIE SSNALVQDSD 240
KEGNVSQSDL KLQFLKEAQS YLKKLSIKGY SDAQYLLADG YSSGAFGKIE NKEAFVLFQA 300
AAKHGHIESA YRASHCLEEG LGTTRDSRKS VNFLKFAASR NHPSAMYKLG LYSFYGRMGL 360
PTDVNTKLNG VKWLSRAAAR ANELTAAAPY ELAKIYHEGF LDVVIPDEKY AMELYIQAAS 420
LGHVPSATLL AQIYETGNDT VGQDTSLSVH YYTQAALKGD SVAMLGLCAW YLLGAEPAFE 480
KDENEAFQWA LRAANAGLPK AQFTLGYFYE HGKGCDRNME YAWKWYEKAA GNEDKRAINK 540
LRSRDGGLAS IGKKQHKKNK SISTLNLFST VDSQTSNVGS NSRVSSKSET FFTGNPKRDR 600
EPQGLQINMN SNTNRNGIKT GSDTSIRKSS SSAKGMSREV AEQSMAAKQE VSLSNMGSSN 660
MIRKDFPAVK TESKKPTSLK NKKDKQGKKK KDCVIM 696 
Gene Ontology
 GO:0005935; C:cellular bud neck; IDA:SGD.
 GO:0000131; C:incipient cellular bud site; IDA:SGD.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0008047; F:enzyme activator activity; IMP:SGD.
 GO:0034221; P:fungal-type cell wall chitin biosynthetic process; IMP:SGD. 
Interpro
 IPR006597; Sel1-like.
 IPR011990; TPR-like_helical. 
Pfam
 PF08238; Sel1 
SMART
 SM00671; SEL1 
PROSITE
  
PRINTS