UniProt Accession

 NDRG3_HUMAN; Q9UGV2; A2A2S8; E1P5U7; E1P5U8; Q5TH32; Q96PL8; Q96SM2; Q9BXY7; Q9H3N7; Q9H411; Q9H8J6 

Genbank Protein ID

 AB044943; AF251054; AF308609; AK023618; AK027665; AL031662; AL132768; AL132768; AL031662; AL132768; AL031662; AL031662; AL132768; CH471077; CH471077; CH471077; CH471077; BC136489 

Genbank Nucleotide ID

 BAB20067.1; AAK34944.1; AAL08807.1; BAB14620.1; BAB55277.1; CAI21399.1; CAI21399.1; CAI21461.1; CAI21461.1; CAM28251.1; CAM28251.1; CAM45843.1; CAM45843.1; EAW76112.1; EAW76109.1; EAW76114.1; EAW76115.1; AAI36490.1 

Protein Name

 Protein NDRG3 

Protein Synonyms/Alias

 N-myc downstream-regulated gene 3 protein 

Gene Name

 NDRG3 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
13	DVQLTEIKPLLNDKN	ubiquitination	[1, 2]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789] 

Functional Description

  

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine.
 MOD_RES 322 322 Phosphothreonine.
 MOD_RES 331 331 Phosphoserine.
 MOD_RES 334 334 Phosphoserine (By similarity).
 MOD_RES 335 335 Phosphoserine.
 MOD_RES 352 352 Phosphoserine.
 MOD_RES 374 374 Phosphoserine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 375 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:UniProtKB.
 GO:0030154; P:cell differentiation; NAS:UniProtKB.
 GO:0030308; P:negative regulation of cell growth; NAS:UniProtKB.
 GO:0007283; P:spermatogenesis; NAS:UniProtKB. 

Interpro

 IPR004142; Ndr. 

Pfam

 PF03096; Ndr 

SMART

  

PROSITE

  

PRINTS