UniProt Accession

 PPIB_ECOLI; P23869; P78052; Q2MBQ4 

Genbank Protein ID

 M55430; U00096; AP009048; X59293 

Genbank Nucleotide ID

 AAA23453.1; AAC73627.1; BAE76302.1; CAA41982.1 

Protein Name

 Peptidyl-prolyl cis-trans isomerase B 

Protein Synonyms/Alias

 PPIase B; Rotamase B 

Gene Name

 ppiB 

Gene Synonyms/Alias

 b0525; JW0514 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
14	NHGDIVIKTFDDKAP	acetylation	[1, 2]
19	VIKTFDDKAPETVKN	acetylation	[1, 2]
25	DKAPETVKNFLDYCR	acetylation	[1, 2]
60	GGFEPGMKQKATKEP	acetylation	[2]
60	GGFEPGMKQKATKEP	pupylation	[3]
65	GMKQKATKEPIKNEA	acetylation	[2]
69	KATKEPIKNEANNGL	acetylation	[1, 2]
77	NEANNGLKNTRGTLA	acetylation	[2]
137	MDVVDKIKGVATGRS	acetylation	[1]
152	GMHQDVPKEDVIIES	acetylation	[2]

Reference

 [1] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111]
 [2] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [3] Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coli.
 Cerda-Maira FA, McAllister F, Bode NJ, Burns KE, Gygi SP, Darwin KH.
 EMBO Rep. 2011 Jul 8;12(8):863-70. [PMID: 21738222] 

Functional Description

 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. 

Sequence Annotation

 DOMAIN 1 162 PPIase cyclophilin-type.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Isomerase; Reference proteome; Rotamase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 164 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:EcoCyc.
 GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IDA:EcoCyc.
 GO:0006457; P:protein folding; IEA:UniProtKB-KW. 

Interpro

 IPR002130; Cyclophilin-like_PPIase_dom.
 IPR020892; Cyclophilin-type_PPIase_CS. 

Pfam

 PF00160; Pro_isomerase 

SMART

  

PROSITE

 PS00170; CSA_PPIASE_1
 PS50072; CSA_PPIASE_2 

PRINTS

 PR00153; CSAPPISMRASE.