CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002593
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Succinate dehydrogenase flavoprotein subunit 
Protein Synonyms/Alias
  
Gene Name
 sdhA 
Gene Synonyms/Alias
 citF; BSU28440 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
38LFSIVPVKRSHSVCAacetylation[1]
267VWTYKDGKPWYFLEEacetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065] 
Functional Description
  
Sequence Annotation
 NP_BIND 10 15 FAD (By similarity).
 NP_BIND 33 48 FAD (By similarity).
 NP_BIND 391 392 FAD (By similarity).
 ACT_SITE 285 285 Proton acceptor (By similarity).
 BINDING 236 236 Substrate (By similarity).
 BINDING 250 250 Substrate (By similarity).
 BINDING 352 352 Substrate (By similarity).
 BINDING 376 376 FAD (By similarity).
 BINDING 386 386 Substrate (By similarity).
 MOD_RES 41 41 Tele-8alpha-FAD histidine (By  
Keyword
 Cell membrane; Complete proteome; Electron transport; FAD; Flavoprotein; Membrane; Oxidoreductase; Reference proteome; Transport; Tricarboxylic acid cycle. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 586 AA 
Protein Sequence
MSQSSIIVVG GGLAGLMATI KAAESGMAVK LFSIVPVKRS HSVCAQGGIN GAVNTKGEGD 60
SPWEHFDDTV YGGDFLANQP PVKAMCEAAP SIIHLLDRMG VMFNRTPEGL LDFRRFGGTQ 120
HHRTAYAGAT TGQQLLYALD EQVRRYEVAG LVTKYEGWEF LGAVLDDDRT CRGIVAQNLT 180
NMQIESFRSD AVIMATGGPG IIFGKSTNSM INTGSAASIV YQQGAYYANG EFIQIHPTAI 240
PGDDKLRLMS ESARGEGGRV WTYKDGKPWY FLEEKYPAYG NLVPRDIATR EIFDVCVNQK 300
LGINGENMVY LDLSHKDPKE LDIKLGGIIE IYEKFMGDDP RKLPMKIFPA VHYSMGGLWV 360
DYDQMTNIPG LFAAGECDYS MHGGNRLGAN SLLSAIYGGM VAGPNAVKYV NGLESSAEDM 420
SSSLFDAHVK KEEEKWADIM SMDGTENAYV LHKELGEWMT ANVTVVRHND KLLKTDDKIQ 480
ELMERFKKIN INDTTKWSNQ GAMFTRQFSN MLQLARVITL GAYNRNESRG AHYKPDYPER 540
NDDEWLKTTM AKHVSPYEAP EFEYQDVDVS LITPRKRDYS KKKVAK 586 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0000104; F:succinate dehydrogenase activity; IEA:EC.
 GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.
 GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway. 
Interpro
 IPR003953; FAD_bind_dom.
 IPR013027; FAD_pyr_nucl-diS_OxRdtase.
 IPR003952; FRD_SDH_FAD_BS.
 IPR015939; Fum_Rdtase/Succ_DH_flav-like_C.
 IPR011280; Succ_DH/Fum_Rdt_flav_su.
 IPR027477; Succ_DH/fumarate_Rdtase_cat. 
Pfam
 PF00890; FAD_binding_2
 PF02910; Succ_DH_flav_C 
SMART
  
PROSITE
 PS00504; FRD_SDH_FAD_BINDING 
PRINTS
 PR00368; FADPNR.