CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028503
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein 4.1 
Protein Synonyms/Alias
  
Gene Name
 Epb4.1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
71VYECVVEKHAKGQDLubiquitination[1]
204KLAPNQTKELEEKVMubiquitination[1]
209QTKELEEKVMELHKSubiquitination[1]
215EKVMELHKSYRSMTPubiquitination[1]
234LEFLENAKKLSMYGVubiquitination[1]
235EFLENAKKLSMYGVDubiquitination[1]
421EGPGAPIKKTPKEAVubiquitination[1]
550SDTANAVKSEIPTKDubiquitination[1]
556VKSEIPTKDVPIVHTubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 667 AA 
Protein Sequence
PAQEEHREDP DSETKEGEGI EECSGTEVKE DPESRAEREP EASQKPVRRH RNMHCKVSLL 60
DDTVYECVVE KHAKGQDLLK RVCEHLNLLE EDYFGLALWD SATSKTWLDS AKEIKKQVRG 120
VPWNFTFNVK FYPPDPAQLT EDITRYYLCL QLRQDIVAGR LPCSFATLAL LGSYTIQSEL 180
GDYDPELHGM DYVSDFKLAP NQTKELEEKV MELHKSYRSM TPAQADLEFL ENAKKLSMYG 240
VDLHKAKDLE GVDIILGVCS SGLLVYKDKL RINRFPWPKV LKISYKRSSF FIKIRPGEQE 300
HYESTIGFKL PSYRAAKKLW KVCVEHHTFF RLTSTDTIPK SKFLALGSKF RYSGRTQAQT 360
RQASALIDRP APHFERTASK RASRSLDGAA AAESTDRSPR PTSAPAIAQS QVTEGPGAPI 420
KKTPKEAVKV EEKRGEEPAE PAEPEPTEAW KKKRERLDGE NIYIRHSNLM LEDLDKSQEE 480
IKKHHASISE LKKNFMESVP EPRPSEWDKR LSTHSPFRTL NINGQVPTGD GPPLVKTQTV 540
TISDTANAVK SEIPTKDVPI VHTETKTITY EAAQTEDSNG DLDPGVLLTA QTITSETTSS 600
TTTTQITKTV KGGISETRIE KRIVITGDAD IDHDQVLVQA IKEAKEQHPD MSVTKVVVHQ 660
ETEISEE 667 
Gene Ontology
 GO:0015629; C:actin cytoskeleton; ISS:MGI.
 GO:0030863; C:cortical cytoskeleton; IDA:MGI.
 GO:0019898; C:extrinsic to membrane; IEA:InterPro.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0003779; F:actin binding; ISS:MGI.
 GO:0030507; F:spectrin binding; ISS:MGI.
 GO:0005198; F:structural molecule activity; IEA:InterPro.
 GO:0030036; P:actin cytoskeleton organization; ISS:MGI.
 GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
 GO:0032092; P:positive regulation of protein binding; IGI:MGI.
 GO:0008360; P:regulation of cell shape; ISS:MGI. 
Interpro
 IPR008379; Band_4.1_C.
 IPR019749; Band_41_domain.
 IPR019750; Band_41_fam.
 IPR021187; Band_41_protein.
 IPR000798; Ez/rad/moesin_like.
 IPR014847; FERM-adjacent.
 IPR014352; FERM/acyl-CoA-bd_prot_3-hlx.
 IPR019748; FERM_central.
 IPR019747; FERM_CS.
 IPR000299; FERM_domain.
 IPR018979; FERM_N.
 IPR018980; FERM_PH-like_C.
 IPR011993; PH_like_dom.
 IPR007477; SAB_dom. 
Pfam
 PF05902; 4_1_CTD
 PF08736; FA
 PF09380; FERM_C
 PF00373; FERM_M
 PF09379; FERM_N
 PF04382; SAB 
SMART
 SM00295; B41 
PROSITE
 PS00660; FERM_1
 PS00661; FERM_2
 PS50057; FERM_3 
PRINTS
 PR00935; BAND41.
 PR00661; ERMFAMILY.