CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-039828
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lipopolysaccharide-responsive and beige-like anchor protein 
Protein Synonyms/Alias
  
Gene Name
 LRBA 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
1487PLGKSAAKSPVDIVTubiquitination[1]
1679VSKNVNVKDILRSLVubiquitination[1]
1806RLEHALEKAAPLLREubiquitination[1]
2196ASPRQLFKASNMTQRubiquitination[1]
2260TNFRDLSKPIGALNPubiquitination[1]
2268PIGALNPKRAAFFAEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2852 AA 
Protein Sequence
MASEDNRVPS PPPTGDDGGG GGREETPTEG GALSLKPGLP IRGIRMKFAV LTGLVEVGEV 60
SNRDIVETVF NLLVGGQFDL EMNFIIQEGE SINCMVDLLE KCDITCQAEV WSMFTAILKK 120
SIRNLQVCTE VGLVEKVLGK IEKVDNMIAD LLVDMLGVLA SYNLTVRELK LFFSKLQGDK 180
GRWPPHAGKL LSVLKHMPQK YGPDAFFNFP GKSAAAIALP PIAKWPYQNG FTFHTWLRMD 240
PVNNINVDKD KPYLYCFRTS KGLGYSAHFV GGCLIVTSIK SKGKGFQHCV KFDFKPQKWY 300
MVTIVHIYNR WKNSELRCYV NGELASYGEI TWFVNTSDTF DKCFLGSSET ADANRVFCGQ 360
MTAVYLFSEA LNAAQIFAIY QLGLGYKGTF KFKAESDLFL AEHHKLLLYD GKLSSAIAFT 420
YNPRATDAQL CLESSPKDNP SIFVHSPHAL MLQDVKAVLT HSIQSAMHSI GGVQVLFPLF 480
AQLDYRQYLS DEIDLTICST LLAFIMELLK NSIAMQEQML ACKGFLVIGY SLEKSSKSHV 540
SRAVLELCLA FSKYLSNLQN GMPLLKQLCD HVLLNPAIWI HTPAKVQLML YTYLSTEFIG 600
TVNIYNTIRR VGTVLLIMHT LKYYYWAVNP QDRSGITPKG LDGPRPNQKE MLSLRAFLLM 660
FIKQLVMKDS GVKEDELQAI LNYLLTMHED DNLMDVLQLL VALMSEHPNS MIPAFDQRNG 720
LRVIYKLLAS KSEGIRVQAL KAMGYFLKHL APKRKAEVML GHGLFSLLAE RLMLQTNLIT 780
MTTYNVLFEI LIEQIGTQVI HKQHPDPDSS VKIQNPQILK VIATLLRNSP QCPESMEVRR 840
AFLSDMIKLF NNSRENRRSL LQCSVWQEWM LSLCYFNPKN SDEQKITEMV YAIFRILLYH 900
AVKYEWGGWR VWVDTLSITH SKVTFEIHKE NLANIFREQQ GKVDEEIGLC SSTSVQAASG 960
IRRDINVSVG SQQPDTKDSP VCPHFTTNGN ENSSIEKTSS LESASNIELQ TTNTSYEEMK 1020
AEQENQELPD EGTLEETLTN ETRNADDLEV SSDIIEAVAI SSNSFITTGK DSMTVSEVTA 1080
SISSPSEEDA SEMPEFLDKS IVEEEEDDDY VELKVEGSPT EEANLPTELQ DNSLSPAASE 1140
AGEKLDMFGN DDKLIFQEGK PVTEKQTDTE TQDSKDSGIQ TMTASGSSAM SPETTVSQIA 1200
VESDLGQMLE EGKKATNLTR ETKLINDCHG SVSEASSEQK IAKLDVSNVA TDTERLELKA 1260
SPNVEAPQPH RHVLEISRQH EQPGQGIAPD AVNGQRRDSR STVFRIPEFN WSQMHQRLLT 1320
DLLFSIETDI QMWRSHSTKT VMDFVNSSDN VIFVHNTIHL ISQVMDNMVM ACGGILPLLS 1380
AATSATHELE NIEPTQGLSI EASVTFLQRL ISLVDVLIFA SSLGFTEIEA EKSMSSGGIL 1440
RQCLRLVCAV AVRNCLECQQ HSQLKTRGDK ALKPMHSLIP LGKSAAKSPV DIVTGGISPV 1500
RDLDRLLQDM DINRLRAVVF RDIEDSKQAQ FLALAVVYFI SVLMVSKYRD ILEPQNERHS 1560
QSCTETGSEN ENVSLSEITP AAFSTLTTAS VEESESTSSA RRRDSGIGEE TATGLGSHVE 1620
VTPHTAPPGV SAGPDAISEV LSTLSLEVNK SPETKNDRGN DLDTKATPSV SVSKNVNVKD 1680
ILRSLVNIPA DGVTVDPALL PPACLGALGD LSVEQPVQFR SFDRSVIVAA KKSAVSPSTF 1740
NTSIPTNAVS VVSSVDSAQA SDMGGESPGS RSSNAKLPSV PTVDSVSQDP VSNMSITERL 1800
EHALEKAAPL LREIFVDFAP FLSRTLLGSH GQELLIEGTS LVCMKSSSSV VELVMLLCSQ 1860
EWQNSIQKNA GLAFIELVNE GRLLSQTMKD HLVRVANEAE FILSRQRAED IHRHAEFESL 1920
CAQYSADKRE DEKMCDHLIR AAKYRDHVTA TQLIQKIINI LTDKHGAWGN SAVSRPLEFW 1980
RLDYWEDDLR RRRRFVRNPL GSTHPEATLK TAVEHATDED ILAKGKQSIR SQALGNQNSE 2040
NEILLEGDDD TLSSVDEKDL ENLAGPVSLS TPAQLVAPSV VVKGTLSVTS SELYFEVDEE 2100
DPNFKKIDPK ILAYTEGLHG KWLFTEIRSI FSRRYLLQNT ALEIFMANRV AVMFNFPDPA 2160
TVKKVVNYLP RVGVGTSFGL PQTRRISLAS PRQLFKASNM TQRWQHREIS NFEYLMFLNT 2220
IAGRSYNDLN QYPVFPWVIT NYESEELDLT LPTNFRDLSK PIGALNPKRA AFFAERYESW 2280
EDDQVPKFHY GTHYSTASFV LAWLLRIEPF TTYFLNLQGG KFDHADRTFS SISRAWRNSQ 2340
RDTSDIKELI PEFYYLPEMF VNFNNYNLGV MDDGTVVSDV ELPPWAKTSE EFVHINRLAL 2400
ESEFVSCQLH QWIDLIFGYK QQGPEAVRAL NVFYYLTYEG AVNLNSITDP VLREAVEAQI 2460
RSFGQTPSQL LIEPHPPRGS AMQVSPLMFT DKAQQDVIMV LKFPSNSPVT HVAANTQPGL 2520
ATPAVITVTA NRLFAVNKWH NLPAHQGAVQ DQPYQLPVEI DPLIASNTGM HRRQITDLLD 2580
QSIQVHSQCF VITSDNRYIL VCGFWDKSFR VYSTDTGRLI QVVFGHWDVV TCLARSESYI 2640
GGNCYILSGS RDATLLLWYW NGKCSGIGDN PGSETAAPRA ILTGHDYEVT CAAVCAELGL 2700
VLSGSQEGPC LIHSMNGDLL RTLEGPENCL KPKLIQASRE GHCVIFYENG LFCTFSVNGK 2760
LQATMETDDN IRAIQLSRDG QYLLTGGDRG VVVVRQVSDL KQLFAYPGCD AGIRAMALSY 2820
DQRCIISGMA SGSIVLFYND FNRWHHEYQT RY 2852 
Gene Ontology
  
Interpro
 IPR016024; ARM-type_fold.
 IPR000409; BEACH_dom.
 IPR008985; ConA-like_lec_gl_sf.
 IPR013320; ConA-like_subgrp.
 IPR010508; DUF1088.
 IPR023362; PH-BEACH_dom.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF02138; Beach
 PF06469; DUF1088
 PF00400; WD40 
SMART
 SM01026; Beach
 SM00320; WD40 
PROSITE
 PS50197; BEACH 
PRINTS