CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040373
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 PAX3- and PAX7-binding protein 1 
Protein Synonyms/Alias
  
Gene Name
 Paxbp1 
Gene Synonyms/Alias
 Gcfc1 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
217RRIVFSVKEKSQRQKacetylation[1, 2]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 450 AA 
Protein Sequence
XPPSAHHPGL GAEAGGGISG GAEPGNGLKP RKRPRENKEV PRASLLSFQD EEEENEEVFK 60
VKKSSYSKKI VKLLKKEYKE DLEKSKIKTE LNTAADSDQP LDKTCHAKDT NPEDGVVISE 120
HGEDEMDMES EKEEEKPKAG GAFSNALSSL NVLRPGEIPD AAFIHAARKK RQLARELGDF 180
TPHDSEPGKG RLVREDENDA SDDEDDDEKR RIVFSVKEKS QRQKIAEEIG IEGSDDDALV 240
TGEQDEELSR WEQEQIRKGI NIPQVQASQP SEVNVYYQNT YQTMPYGASY GIPYSYTAYG 300
SSDAKSQKTD NTVPFKTPSN EMAPVTIDLV KRQLKDRLDS MKELHKTNQQ QHEKHLQSRV 360
DSTRAIERLE GSSGGIGERY KFLQEMRGYV QDLLECFSEK VPLINELESA IHQLYKQRAS 420
RLVQRRQDDI KDESSEFSSH SSQSILKIKL 450 
Gene Ontology
 GO:0005634; C:nucleus; IDA:MGI.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro.
 GO:0031062; P:positive regulation of histone methylation; IDA:MGI.
 GO:2000288; P:positive regulation of myoblast proliferation; IMP:MGI.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.
 GO:0014842; P:regulation of satellite cell proliferation; IMP:MGI. 
Interpro
 IPR012890; GCFC. 
Pfam
  
SMART
  
PROSITE
  
PRINTS