UniProt Accession

 D3Z6I7_MOUSE; D3Z6I7 

Genbank Protein ID

 AC102668; AC153627 

Genbank Nucleotide ID

  

Protein Name

 Protein Cald1 

Protein Synonyms/Alias

  

Gene Name

 Cald1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
113	QEALERQKEFDPTIT	ubiquitination	[1]
284	GGRASGDKEAEGAPQ	acetylation	[2]
331	ALELEELKKKREERR	acetylation	[2, 3]
367	EEEKRRLKEEIERRR	acetylation	[4]
393	EDGLSEDKKPFKCFT	acetylation	[4]
394	DGLSEDKKPFKCFTP	acetylation	[2, 4]
397	SEDKKPFKCFTPKGS	acetylation	[4]
407	TPKGSSLKIEERAEF	acetylation	[4]
417	ERAEFLNKSVQKSGV	acetylation	[2, 4]
417	ERAEFLNKSVQKSGV	succinylation	[2]
417	ERAEFLNKSVQKSGV	ubiquitination	[1]
435	HQAAVVSKIDSRLEQ	acetylation	[4]
454	IEGTKASKPMKPAAS	acetylation	[4]
474	AEGVRNIKSMWEKGS	acetylation	[2]
479	NIKSMWEKGSVFSAP	acetylation	[4]
513	RINEWLTKSPDGNKS	acetylation	[4]
542	GKRNLWEKQSVDKVT	acetylation	[4]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 554 AA 

Protein Sequence

Gene Ontology

 GO:0030478; C:actin cap; IDA:MGI.
 GO:0016020; C:membrane; IDA:MGI.
 GO:0003779; F:actin binding; TAS:MGI.
 GO:0006936; P:muscle contraction; IEA:InterPro.
 GO:0006940; P:regulation of smooth muscle contraction; TAS:MGI. 

Interpro

 IPR006017; Caldesmon.
 IPR006018; Caldesmon_LSP. 

Pfam

 PF02029; Caldesmon 

SMART

  

PROSITE

  

PRINTS

 PR01076; CALDESMON.