UniProt Accession

 E9KL35_HUMAN; E9KL35 

Genbank Protein ID

 GU727632 

Genbank Nucleotide ID

 ADU87634.1 

Protein Name

 Epididymis tissue sperm binding protein Li 3a 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
12	MTLRGTLKGHNGWVT	ubiquitination	[1]
38	ILSASRDKTIIMWKL	ubiquitination	[1, 2]
44	DKTIIMWKLTRDETN	ubiquitination	[1, 2]
106	RRFVGHTKDVLSVAF	ubiquitination	[1, 2]
130	GSRDKTIKLWNTLGV	ubiquitination	[1, 2]
139	WNTLGVCKYTVQDES	ubiquitination	[1]
172	IVSCGWDKLVKVWNL	ubiquitination	[1, 2]
175	CGWDKLVKVWNLANC	ubiquitination	[1, 2]
183	VWNLANCKLKTNHIG	ubiquitination	[1, 2]
257	AATGPSIKIWDLEGK	ubiquitination	[1]
271	KIIVDELKQEVISTS	ubiquitination	[1, 2]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Repeat; WD repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 317 AA 

Protein Sequence

Gene Ontology

 GO:0030425; C:dendrite; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0015935; C:small ribosomal subunit; IEA:Compara.
 GO:0008200; F:ion channel inhibitor activity; IEA:Compara.
 GO:0017148; P:negative regulation of translation; IEA:Compara.
 GO:0090003; P:regulation of establishment of protein localization to plasma membrane; IEA:Compara. 

Interpro

 IPR020472; G-protein_beta_WD-40_rep.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 

Pfam

 PF00400; WD40 

SMART

 SM00320; WD40 

PROSITE

 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 

PRINTS

 PR00320; GPROTEINBRPT.