CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034080
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Troponin I, cardiac muscle 
Protein Synonyms/Alias
  
Gene Name
 Tnni3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
37YATEPHAKKKSKISAubiquitination[1]
51ASRKLQLKTLMLQIAubiquitination[1]
59TLMLQIAKQEMEREAubiquitination[1]
107QLHARVDKVDEERYDubiquitination[1]
118ERYDVEAKVTKNITEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 125 AA 
Protein Sequence
MADESSDAAG EPQPAPAPVR RRSSANYRAY ATEPHAKKKS KISASRKLQL KTLMLQIAKQ 60
EMEREAEERR GEKGRVLRTR CQPLELDGLG FEELQDLCRQ LHARVDKVDE ERYDVEAKVT 120
KNITE 125 
Gene Ontology
 GO:0030017; C:sarcomere; IDA:MGI.
 GO:0005861; C:troponin complex; IEA:Compara.
 GO:0019855; F:calcium channel inhibitor activity; IEA:Compara.
 GO:0060048; P:cardiac muscle contraction; IEA:Compara.
 GO:0006874; P:cellular calcium ion homeostasis; IDA:MGI.
 GO:0007507; P:heart development; IDA:MGI.
 GO:0032780; P:negative regulation of ATPase activity; IEA:Compara.
 GO:0006937; P:regulation of muscle contraction; IDA:MGI.
 GO:0006940; P:regulation of smooth muscle contraction; IEA:Compara.
 GO:0001980; P:regulation of systemic arterial blood pressure by ischemic conditions; IMP:MGI.
 GO:0006941; P:striated muscle contraction; IDA:MGI.
 GO:0001570; P:vasculogenesis; IDA:MGI.
 GO:0055010; P:ventricular cardiac muscle tissue morphogenesis; IEA:Compara. 
Interpro
 IPR001978; Troponin.
 IPR021666; Troponin-I_N. 
Pfam
 PF00992; Troponin
 PF11636; Troponin-I_N 
SMART
  
PROSITE
  
PRINTS