| Tag | Content |
|---|
| CPLM ID | CPLM-006701 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Phosphoglucomutase-2 |
Protein Synonyms/Alias | PGM 2; Glucose phosphomutase 2 |
Gene Name | PGM2 |
Gene Synonyms/Alias | GAL5; YMR105C; YM9718.04C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 428 | IQNEFWAKYGRTFFT | acetylation | [1] | | 449 | VETEKANKIVDQLRA | acetylation | [1] | | 537 | DDKSQYQKTAEEYLK | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | This enzyme participates in both the breakdown and synthesis of glucose. Can also act on mannose. |
Sequence Annotation | ACT_SITE 119 119 Phosphoserine intermediate (By
METAL 119 119 Magnesium; via phosphate group (By
METAL 290 290 Magnesium (By similarity).
METAL 292 292 Magnesium (By similarity).
METAL 294 294 Magnesium (By similarity).
MOD_RES 111 111 Phosphothreonine.
MOD_RES 117 117 Phosphothreonine.
MOD_RES 119 119 Phosphoserine. |
Keyword | Carbohydrate metabolism; Complete proteome; Cytoplasm; Glucose metabolism; Isomerase; Magnesium; Metal-binding; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 569 AA |
Protein Sequence | MSFQIETVPT KPYEDQKPGT SGLRKKTKVF KDEPNYTENF IQSIMEAIPE GSKGATLVVG 60
GDGRYYNDVI LHKIAAIGAA NGIKKLVIGQ HGLLSTPAAS HIMRTYEEKC TGGIILTASH 120
NPGGPENDMG IKYNLSNGGP APESVTNAIW EISKKLTSYK IIKDFPELDL GTIGKNKKYG 180
PLLVDIIDIT KDYVNFLKEI FDFDLIKKFI DNQRSTKNWK LLFDSMNGVT GPYGKAIFVD 240
EFGLPADEVL QNWHPSPDFG GMHPDPNLTY ASSLVKRVDR EKIEFGAASD GDGDRNMIYG 300
YGPSFVSPGD SVAIIAEYAA EIPYFAKQGI YGLARSFPTS GAIDRVAKAH GLNCYEVPTG 360
WKFFCALFDA KKLSICGEES FGTGSNHVRE KDGVWAIMAW LNILAIYNKH HPENEASIKT 420
IQNEFWAKYG RTFFTRYDFE KVETEKANKI VDQLRAYVTK SGVVNSAFPA DESLKVTDCG 480
DFSYTDLDGS VSDHQGLYVK LSNGARFVLR LSGTGSSGAT IRLYIEKYCD DKSQYQKTAE 540
EYLKPIINSV IKFLNFKQVL GTEEPTVRT 569 |
Gene Ontology | GO:0005829; C:cytosol; IBA:RefGenome. GO:0000287; F:magnesium ion binding; IEA:InterPro. GO:0004614; F:phosphoglucomutase activity; IMP:SGD. GO:0006874; P:cellular calcium ion homeostasis; IMP:SGD. GO:0019388; P:galactose catabolic process; IMP:SGD. GO:0019255; P:glucose 1-phosphate metabolic process; IMP:SGD. GO:0051156; P:glucose 6-phosphate metabolic process; ISS:SGD. GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW. GO:0005978; P:glycogen biosynthetic process; IGI:SGD. GO:0005992; P:trehalose biosynthetic process; IGI:SGD. GO:0006011; P:UDP-glucose metabolic process; IGI:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |