CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020089
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Protein orai-3 
Protein Synonyms/Alias
 Transmembrane protein 142C 
Gene Name
 ORAI3 
Gene Synonyms/Alias
 TMEM142C 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
2******MKGGEGDAGubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
 Key regulator or component of store-operated Ca(2+) channel and transcription factor NFAT nuclear import (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MKGGEGDAGE QAPLNPEGES PAGSATYREF VHRGYLDLMG ASQHSLRALS WRRLYLSRAK 60
LKASSRTSAL LSGFAMVAMV EVQLESDHEY PPGLLVAFSA CTTVLVAVHL FALMVSTCLL 120
PHIEAVSNIH NLNSVHQSPH QRLHRYVELA WGFSTALGTF LFLAEVVLVG WVKFVPIGAP 180
LDTPTPMVPT SRVPGTLAPV ATSLSPASNL PRSSASAAPS QAEPACPPRQ ACGGGGAHGP 240
GWQAAMASTA IMVPVGLVFV AFALHFYRSL VAHKTDRYKQ ELEELNRLQG ELQAV 295 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR012446; CRAC_channel. 
Pfam
 PF07856; Orai-1 
SMART
  
PROSITE
  
PRINTS