Tag | Content |
---|
CPLM ID | CPLM-006048 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Tricarboxylate transport protein, mitochondrial |
Protein Synonyms/Alias | Citrate transport protein; CTP; Solute carrier family 25 member 1; Tricarboxylate carrier protein |
Gene Name | Slc25a1 |
Gene Synonyms/Alias | Slc20a3 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
---|
149 | PMETVKVKFIHDQTS | acetylation | [1] | 190 | GLTATVLKQGSNQAI | acetylation | [1] | 255 | MQGLEAHKYRNTLDC | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | Involved in citrate-H(+)/malate exchange. Important for the bioenergetics of hepatic cells as it provides a carbon source for fatty acid and sterol biosyntheses, and NAD(+) for the glycolytic pathway. |
Sequence Annotation | REPEAT 23 111 Solcar 1. REPEAT 122 208 Solcar 2. REPEAT 218 303 Solcar 3. |
Keyword | Complete proteome; Direct protein sequencing; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Repeat; Transit peptide; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 311 AA |
Protein Sequence | MAAPRAPRAL TAAAPGSGKA KLTHPGKAIL AGGLAGGIEI CITFPTEYVK TQLQLDERAN 60 PPRYRGIGDC VRQTVRSHGV LGLYRGLSSL LYGSIPKAAV RFGMFEFLSN HMRDAQGRLD 120 SRRGLLCGLG AGVAEAVVVV CPMETVKVKF IHDQTSSNPK YRGFFHGVRE IVREQGLKGT 180 YQGLTATVLK QGSNQAIRFF VMTSLRNWYQ GDNPNKPMNP LITGVFGAVA GAASVFGNTP 240 LDVIKTRMQG LEAHKYRNTL DCGVQILKNE GPKAFYKGTV PRLGRVCLDV AIVFVIYDEV 300 VKLLNKVWKT D 311 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0015137; F:citrate transmembrane transporter activity; TAS:RGD. GO:0006843; P:mitochondrial citrate transport; TAS:RGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |