| Tag | Content |
|---|
| CPLM ID | CPLM-022654 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Gamma-adducin |
Protein Synonyms/Alias | Adducin-like protein 70 |
Gene Name | Add3 |
Gene Synonyms/Alias | Addl |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 21 | PPPSMPHKERYFDRI | ubiquitination | [1] | | 401 | VREKPRHKSDVEIPA | ubiquitination | [1] | | 426 | SAPLSPLKFMAQRQQ | ubiquitination | [1] | | 484 | VSSGTPIKIEDPNQF | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Binds to calmodulin. |
Sequence Annotation | REGION 684 701 Interaction with calmodulin (Potential).
MOD_RES 2 2 N-acetylserine (By similarity).
MOD_RES 42 42 Phosphoserine (By similarity).
MOD_RES 64 64 Phosphoserine (By similarity).
MOD_RES 402 402 Phosphoserine.
MOD_RES 423 423 Phosphoserine (By similarity).
MOD_RES 442 442 Phosphoserine (By similarity).
MOD_RES 673 673 Phosphoserine.
MOD_RES 677 677 Phosphoserine.
MOD_RES 681 681 Phosphoserine.
MOD_RES 683 683 Phosphoserine; by PKC (By similarity). |
Keyword | Acetylation; Actin-binding; Alternative splicing; Calmodulin-binding; Cell membrane; Complete proteome; Cytoplasm; Cytoskeleton; Membrane; Phosphoprotein; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 706 AA |
Protein Sequence | MSSDTSPAVV TTPPPPSMPH KERYFDRINE SDPEYLRERN MSPDLRQDFN MMEQRKRVTQ 60
ILQSPAFRED LECLIQEQMK KGHNPSGLLA LQQIADYIVT SSFSGFSSPS LSLGMVTPIN 120
DLPGADTSSY VKGEKLTRCK LASLYRLADL FGWAHLANTY ISVRISKEQD HIIIIPRGLS 180
FSEATASTLV KVNIIGEVVD QGSTDLKIDH TGFSPHAAIY STRPDVKCVI HIHTLATAAV 240
SSMKCGILPI SQESLILGDV AYYDYQGSLD EEEERIELQK VLGPSCKVLV LRNHGMVALG 300
ETLEEAFHYI FNVQMACEIQ VQAVAGAGGV DNLLVLDLQK YKAFTHGVAM SGGGGVNMAS 360
HQKWKVGEIE FEGLMRTLDN LGYRTGYAYR HPLVREKPRH KSDVEIPATV TAFSFEDDSA 420
PLSPLKFMAQ RQQREKTRWL NSPNTYMKVN VPEESRNGET SPRTKITWMK AEDSSKVSSG 480
TPIKIEDPNQ FVPLNTNPTE VLEKRNKIRE QNRYDLKTAG PQSQLLAGIV VDKPPSTMQF 540
DDDDQGPPAP PNPFSHLLEG ELEEYTKTIE RKQQGLDDAE QGSLSDDAAS VSQIQSQTQS 600
PQSVPERLEE NHELFSKSFT SMDAPVMIMN GKDEMHDVED ELAQRVSRLT TSTTIENIEI 660
TIKSPERTEE VLSPDGSPSK SPSKKKKKFR TPSFLKKNKK KEKVEA 706 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |