CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031234
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RING finger protein 214 
Protein Synonyms/Alias
 cDNA FLJ58281 
Gene Name
 RNF214 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
91RYQEVLDKQRQVENQubiquitination[1]
104NQLQVQLKQLQQRREubiquitination[1, 2]
143KKIEKEKKEFLQKEQubiquitination[2]
176EMELDRLKNQDGEINubiquitination[1]
195EETERAWKAEILSLEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 548 AA 
Protein Sequence
MAASEVAGVV ANAPSPPESS SLCASKSDEG LPDGLSTKDS AQKQKNSPLL STDFKTADSE 60
VNTDQDIEKN LDKMMTERTL LKERYQEVLD KQRQVENQLQ VQLKQLQQRR EEEMKNHQEI 120
LKAIQDVTIK REETKKKIEK EKKEFLQKEQ DLKAEIEKLC EKGRREVWEM ELDRLKNQDG 180
EINRNIMEET ERAWKAEILS LESRKELLVL KLEEAEKEAE LHLTYLKSTP PTLETVRSKQ 240
EWETRLNGVR IMKKNVRDQF NSHIQLVRNG AKLSSLPQIP TPTLPPPPSE TDFMLQVFQP 300
SPSLAPRMPF SIGQVTMPMV MPSADPRSLS FPILNPALSQ PSQPSSPLPG SHGRNSPGLG 360
SLVSPHGPHM PPAASIPPPP GLGGVKASAE TPRPQPVDKL EKILEKLLTR FPQCNKAQMT 420
NILQQIKTAR TTMAGLTMEE LIQLVAARLA EHERVAASTQ PLGRIRALFP APLAQISTPM 480
FLPSAQVSYP GRSSHAPATC KLCLMCQKLV QPSELHPMAC THVLHKECIK FWAQTNTNDT 540
CPFCPTLK 548 
Gene Ontology
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001841; Znf_RING.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
  
SMART
 SM00184; RING 
PROSITE
 PS50089; ZF_RING_2 
PRINTS