CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037952
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Histone acetyltransferase KAT5 
Protein Synonyms/Alias
  
Gene Name
 KAT5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46VHYIDFNKRLDEWVTacetylation[1, 2]
98ASAQASGKTLPIPVQacetylation[2, 3]
Reference
 [1] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 269 AA 
Protein Sequence
MGRARRRYFD EGAWLLAAPR ALAEILSVKD ISGRKLFYVH YIDFNKRLDE WVTHERLDLK 60
KIQFPKKEAK TPTKNGLPGS RPGSPEREVP ASAQASGKTL PIPVQITLRF NLPKEREAIP 120
GGEPDQPLSS SSCLQPNHRS TKRKVEVVSP ATPVPSETAP ASVFPQNGAA RRAVAAQPGR 180
KRKSNCLGTD EDSQDSSDGI PSAPRMTGSL VSDRSHDDIV TRMKNIECIE LGRHRLKPWY 240
FSPYPQELTT LPVLYLCEFC LKYGRSLKC 269 
Gene Ontology
 GO:0005634; C:nucleus; IDA:HPA. 
Interpro
 IPR016181; Acyl_CoA_acyltransferase.
 IPR000953; Chromo_domain/shadow.
 IPR016197; Chromodomain-like.
 IPR025995; Tudor-knot. 
Pfam
 PF11717; Tudor-knot 
SMART
 SM00298; CHROMO 
PROSITE
  
PRINTS