CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034252
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Ubiquitin thioesterase OTUB2 
Protein Synonyms/Alias
  
Gene Name
 Otub2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
183AAGFEEHKFRNFFNAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 323 AA 
Protein Sequence
MALPSSLQDL IPRFHLRRHP RGLFCASSCQ RSHTESSGKT PTLPSVLRLV LPTPKSPLVA 60
CSQLRRLLQH PPGRCPSCSH CPIPKPSCLQ SETSFNLISE KCDILSILRD HPENRIYQRK 120
IQELSKRFTS IRKTKGDGNC FYRALGYSYL ESLLGKSREI LKFKERVLQT PNDLLAAGFE 180
EHKFRNFFNA FYSVVELVEK DSSVSSLLKV FNDQSSSDRI VQFLRLLTSA FIRNRADFFR 240
HFIDEEMDIK DFCTHEVEPM AMECDHVQIT ALSQALNIAL QVEYVDEMDT ALNHHVFPEA 300
AIPSVYLLYK TSHYNILYAA EKH 323 
Gene Ontology
 GO:0008242; F:omega peptidase activity; IEA:InterPro.
 GO:0004843; F:ubiquitin-specific protease activity; IEA:Compara.
 GO:0006520; P:cellular amino acid metabolic process; IEA:Compara.
 GO:0071108; P:protein K48-linked deubiquitination; IEA:Compara.
 GO:0070536; P:protein K63-linked deubiquitination; IEA:Compara. 
Interpro
 IPR003323; OTU.
 IPR019400; Peptidase_C65_otubain.
 IPR016615; Ubiquitin_thioesterase_Otubain. 
Pfam
 PF10275; Peptidase_C65 
SMART
  
PROSITE
 PS50802; OTU 
PRINTS