CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020627
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CD2 antigen cytoplasmic tail-binding protein 2 
Protein Synonyms/Alias
 CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2 
Gene Name
 Cd2bp2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
26EISVPKKKLVDPVAAacetylation[1]
44PGSRFKGKHSLDSDEacetylation[1]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337
Functional Description
 Involved in pre-mRNA splicing as component of the U5 snRNP complex that is involved in spliceosome assembly (By similarity). 
Sequence Annotation
 DOMAIN 281 339 GYF.
 MOD_RES 49 49 Phosphoserine.
 MOD_RES 117 117 Phosphoserine (By similarity).
 MOD_RES 196 196 Phosphoserine.  
Keyword
 Complete proteome; Cytoplasm; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 342 AA 
Protein Sequence
MPKRKVTFQG VGDEDGEDEI SVPKKKLVDP VAAAGGPGSR FKGKHSLDSD EEDDDEEGSS 60
KYDILASEDV EGQEAATLPS EGGVRITPFN LQEEMEEGHF DADGNYFLNQ DAQIRDSWLD 120
NIDWVRIKER PPDKHQVSDS EEEDSLGQTP MSAQALLEGL LELLLPRETV AGALRRLGAR 180
GGGKGSNSKG TGRPNSPQRL DRLSGLADQM VARGNLGVYQ ETRERLAMRL KGLGCRAQGS 240
HDPTPPPSLD MFAEEVAEGE LETPTPTQRE EAESAGDGLM DVMWEYKWEN TGDAELYGPF 300
TSAQMQTWVS EGYFPDGVYC RKLDPPGGQF YNSKRIDFEL YT 342 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0016607; C:nuclear speck; IEA:Compara.
 GO:0005682; C:U5 snRNP; IEA:Compara.
 GO:0043021; F:ribonucleoprotein complex binding; IEA:Compara.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 
Interpro
 IPR003169; GYF. 
Pfam
 PF02213; GYF 
SMART
 SM00444; GYF 
PROSITE
 PS50829; GYF 
PRINTS