CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017077
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger CCCH domain-containing protein 3 
Protein Synonyms/Alias
  
Gene Name
 ZC3H3 
Gene Synonyms/Alias
 KIAA0150; ZC3HDC3 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
460STSLPGDKKSGTSPAacetylation[1]
Reference
 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 
Functional Description
  
Sequence Annotation
 ZN_FING 667 695 C3H1-type 1.
 ZN_FING 699 722 C3H1-type 2.
 ZN_FING 723 749 C3H1-type 3.
 ZN_FING 750 777 C3H1-type 4.
 ZN_FING 778 800 C3H1-type 5.
 MOD_RES 408 408 Phosphoserine.
 MOD_RES 918 918 Phosphoserine.
 MOD_RES 920 920 Phosphoserine.  
Keyword
 Alternative splicing; Complete proteome; Metal-binding; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 948 AA 
Protein Sequence
MEEKEILRRQ IRLLQGLIDD YKTLHGNAPA PGTPAASGWQ PPTYHSGRAF SARYPRPSRR 60
GYSSHHGPSW RKKYSLVNRP PGPSDPPADH AVRPLHGARG GQPPVPQQHV LERQVQLSQG 120
QNVVIKVKPP SKSGSASASG AQRGSLEEFE ETPWSDQRPR EGEGEPPRGQ LQPSRPTRAR 180
GTCSVEDPLL VCQKEPGKPR MVKSVGSVGD SPREPRRTVS ESVIAVKASF PSSALPPRTG 240
VALGRKLGSH SVASCAPQLL GDRRVDAGHT DQPVPSGSVG GPARPASGPR QAREASLVVT 300
CRTNKFRKNN YKWVAASSKS PRVARRALSP RVAAENVCKA SAGMANKVEK PQLIADPEPK 360
PRKPATSSKP GSAPSKYKWK ASSPSASSSS SFRWQSEASS KDHASQLSPV LSRSPSGDRP 420
AVGHSGLKPL SGETPLSAYK VKSRTKIIRR RSSTSLPGDK KSGTSPAATA KSHLSLRRRQ 480
ALRGKSSPVL KKTPNKGLVQ VTTHRLCRLP PSRAHLPTKE ASSLHAVRTA PTSKVIKTRY 540
RIVKKTPASP LSAPPFPLSL PSWRARRLSL SRSLVLNRLR PVASGGGKAQ PGSPWWRSKG 600
YRCIGGVLYK VSANKLSKTS GQPSDAGSRP LLRTGRLDPA GSCSRSLASR AVQRSLAIIR 660
QARQRREKRK EYCMYYNRFG RCNRGERCPY IHDPEKVAVC TRFVRGTCKK TDGTCPFSHH 720
VSKEKMPVCS YFLKGICSNS NCPYSHVYVS RKAEVCSDFL KGYCPLGAKC KKKHTLLCPD 780
FARRGACPRG AQCQLLHRTQ KRHSRRAATS PAPGPSDATA RSRVSASHGP RKPSASQRPT 840
RQTPSSAALT AAAVAAPPHC PGGSASPSSS KASSSSSSSS SPPASLDHEA PSLQEAALAA 900
ACSNRLCKLP SFISLQSSPS PGAQPRVRAP RAPLTKDSGK PLHIKPRL 948 
Gene Ontology
 GO:0005634; C:nucleus; IDA:UniProtKB.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006378; P:mRNA polyadenylation; IMP:UniProtKB.
 GO:0016973; P:poly(A)+ mRNA export from nucleus; IMP:UniProtKB.
 GO:0010793; P:regulation of mRNA export from nucleus; IMP:UniProtKB. 
Interpro
 IPR000571; Znf_CCCH. 
Pfam
 PF00642; zf-CCCH 
SMART
 SM00356; ZnF_C3H1 
PROSITE
 PS50103; ZF_C3H1 
PRINTS