CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016817
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CLK4-associating serine/arginine rich protein 
Protein Synonyms/Alias
 Clk4-associating SR-related protein; Serine/arginine-rich splicing factor 16; Splicing factor, arginine/serine-rich 16; Suppressor of white-apricot homolog 2 
Gene Name
 Clasrp 
Gene Synonyms/Alias
 Clasp; Sfrs16; Srsf16; Swap2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
594DKKAAQEKMIQQEHEacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
 Probably functions as an alternative splicing regulator. May regulate the mRNA splicing of genes such as CLK1. May act by regulating members of the CLK kinase family. 
Sequence Annotation
 MOD_RES 285 285 Phosphoserine (By similarity).
 MOD_RES 294 294 Phosphoserine.
 MOD_RES 327 327 Phosphothreonine (By similarity).
 MOD_RES 331 331 Phosphoserine (By similarity).
 MOD_RES 335 335 Phosphoserine (By similarity).
 MOD_RES 541 541 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; mRNA processing; mRNA splicing; Nucleus; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 668 AA 
Protein Sequence
MWHEARKHER KLRGMMVDYK KRAERRREYY EKIKKDPAQF LQVHGRACKV HLDSAVALAA 60
ESPVNMMPWQ GDTNNMIDRF DVRAHLDHIP DYTPPLLTTI SPEQESDERK CNYERYRGLV 120
QNDFAGISEE QCLYQIYIDE LYGGLQRPSE DEKKKLAEKK ASIGYTYEDS TVAEVEKVAE 180
KPEEEESPAE EESNSDEDEV IPDIDVEVDV DELNQEQVAD LNKQATTYGM ADGDFVRMLR 240
KDKEEAEAIK HAKALEEEKA MYSGRRSRRQ RREFREKRLR GRKISPPSYA RRDSPTYDPY 300
KRSPSESSSE SRSRSRSPSP GREEKITFIT SFGGSDEEAA AAAAAAAASG AAPGKPPAPP 360
QTGGPAPGRN ASTRRRSSSS SASRTSSSRS SSRSSSRSRR GYYRSGRHAR SRSRSWSRSR 420
SRSRRYSRSR SRGRRHSDGG SRDGHRYSRS PARRGGYVPR RRSRSRSRSG DRYKRGARGP 480
RHHSSSHSRS SWSLSPSRSR SVTRSGSRSQ SRSRSRSQSH SQSQSHSPSP PREKLTRPAA 540
SPAVGEKLKK TEPAAGKETG AAKPKLTPQE RLKLRMQKAL NRQFKADKKA AQEKMIQQEH 600
ERQEREDELR AMARKIRMKE RERREKEREE WERQYSRQSR SPSPRYSREY SSSRRRSRSR 660
SRSPHYRH 668 
Gene Ontology
 GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
 GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
 GO:0008380; P:RNA splicing; IEA:UniProtKB-KW. 
Interpro
 IPR019147; SWAP_N_domain. 
Pfam
 PF09750; DRY_EERY 
SMART
  
PROSITE
  
PRINTS