| Tag | Content |
|---|
| CPLM ID | CPLM-016136 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar ribonucleoprotein protein MPP10 |
Protein Synonyms/Alias | M phase phosphoprotein 10 |
Gene Name | Mphosph10 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 649 | SSQAFFSKLQDQVKM | acetylation | [1] |
|
Reference | [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways. Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y. Mol Cell. 2013 Jun 27;50(6):919-30. [ PMID: 23806337] |
Functional Description | Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing (By similarity). |
Sequence Annotation | MOD_RES 61 61 Phosphoserine (Potential).
MOD_RES 120 120 Phosphoserine (By similarity).
MOD_RES 140 140 Phosphoserine (By similarity).
MOD_RES 164 164 Phosphoserine.
MOD_RES 168 168 Phosphoserine (By similarity).
MOD_RES 172 172 Phosphoserine.
MOD_RES 244 244 Phosphoserine.
MOD_RES 247 247 Phosphoserine.
MOD_RES 277 277 Phosphoserine (By similarity).
MOD_RES 609 609 N6-acetyllysine (By similarity). |
Keyword | Acetylation; Chromosome; Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosome biogenesis; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 681 AA |
Protein Sequence | MAPRVFRRQT LERCLREIRK ATNRPECFLT IQNGLASNFT SLTKVLYDFN KVLENGRISG 60
SPLQKLEINS FDDEQIWQQL ELQNEPVLQY FQNAVSETVE DEDISLLPEC EDEECEEDAS 120
EVEADNQENL ETDLDEEQLS DEGGDVPKGR DRAKSSRKSD PRKSPVFSDE DSDLDFDIGK 180
LEQQTKMQIK PPGKPREKSV VDDKFFKLSE MESFLEKVEK EEEKRPDGEE EDEEDIDLFE 240
DIDSDESEGG LFGRQKIKSN KSSRNLKYKD FFDPVESDED ITGVDEELGP DEEKEEEEGF 300
AEEADESISD TDEDNDLEED ENSDQHKGSL KRVTFALPDD EAEDTSPLAV KQESDEVKSS 360
FEKRQEKMNE KIASLEKELL DKKPWQLQGE VTAQKRPENS LLEETLHFDH AVRMAPVITE 420
ETTLHLEDII KQRIRDQAWD DVERKEKPKE DAYEYKKRLT LDHEKSKLSL AEIYEQEYLK 480
LNQQKTEEED NPEHVEIQKM MDSLFLKLDA LSNFHFIPKP PVPEIKVVSN LPAITMEEVA 540
PVSVSDAALL APEEIKEKNK AGDLKTAAEK TATDKKRERR KKKYQKRLKI KEKEKRKKLL 600
EKNNPDQSKS SRAAASEKLK QLTKTGKVSL LKDERKDKPL KSSQAFFSKL QDQVKMQIND 660
AKQPEKIKKK KQDISVHKLK L 681 |
Gene Ontology | GO:0005694; C:chromosome; IEA:UniProtKB-SubCell. GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell. GO:0030529; C:ribonucleoprotein complex; IEA:UniProtKB-KW. GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB. GO:0006364; P:rRNA processing; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |