CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040986
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Zinc finger protein 567 
Protein Synonyms/Alias
  
Gene Name
 ZNF567 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
26TKPDVILKLERGEEPubiquitination[1, 2, 3]
55KAEDFLVKFKEHQEKubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 592 AA 
Protein Sequence
MDVMLENYCH LISVGCHMTK PDVILKLERG EEPWTSFAGH TCLEENWKAE DFLVKFKEHQ 60
EKYSRSVVSI NHKKLVKEKS KIYEKTFTLG KNPVNSKNLP PEYDTHGRIL KNVSELIISN 120
LNPARKRLSE YNGYGKSLLS TKQETTHPEV KSHNQSARAF SHNEVLMQYQ KTETPAQSFG 180
YNDCEKSFLQ RGGLITHSRP YKGENPSVYN KKRRATNIEK KHTCNECGKS FCRKSVLILH 240
QGIHSEEKPY QCHQCGNAFR RKSYLIDHQR THTGEKPFVC NECGKSFRLK TALTDHQRTH 300
TGEKSYECLQ CRNAFRLKSH LIRHQRTHTG EKPYECNDCG KSFRQKTTLS LHQRIHTGEK 360
PYICKECGKS FHQKANLTVH QRTHTGEKPY ICNECGKSFS QKTTLALHEK THNEEKPYIC 420
SECGKSFRQK TTLVAHQRTH TGEKSYECPH CGKAFRMKSY LIDHHRTHTG EKPYECNECG 480
KSFSQKTNLN LHQRIHTGEK PYVCNECGKS FRQKATLTVH QKIHTGQKSY ECPQCGKAFS 540
RKSYLIHHQR THTGEKPYKC SECGKCFRQK TNLIVHQRTH TGGEDGLTGC LS 592 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
  
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS