| Tag | Content |
|---|
| CPLM ID | CPLM-020159 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alanyl-tRNA editing protein Aarsd1 |
Protein Synonyms/Alias | Alanyl-tRNA synthetase domain-containing protein 1 |
Gene Name | AARSD1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 239 | ADHLFKLKTTSWELG | ubiquitination | [1] | | 274 | IEQSVNEKIRDRLPV | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Functions in trans to edit the amino acid moiety from incorrectly charged tRNA(Ala) (By similarity). |
Sequence Annotation | METAL 109 109 Zinc (Potential).
METAL 113 113 Zinc (Potential).
METAL 209 209 Zinc (Potential).
METAL 213 213 Zinc (Potential).
MOD_RES 409 409 Phosphoserine (By similarity). |
Keyword | Alternative splicing; Complete proteome; Cytoplasm; Metal-binding; Phosphoprotein; Protein biosynthesis; Reference proteome; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 412 AA |
Protein Sequence | MEFCVEDSTD VHVLIEDHRI VFSCKNADGV ELYNEIEFYA KVNSKDSQDK RSSRSITCFV 60
RKWKEKVAWP RLTKEDIKPV WLSVDFDNWR DWEGDEEMEL AHVEHYAELL KKVSTKRPPP 120
AMDDLDFTTT VVSCCPAELQ TEGSNGKKEV LSGFQVVLED TVLFPEGGGQ PDDRGTINDI 180
SVLRVTRRGE QADHFTQTPL DPGSQVLVRV DWERRFDHMQ QHSGQHLITA VADHLFKLKT 240
TSWELGRFRS AIELDTPSMT AEQVAAIEQS VNEKIRDRLP VNVRELSLDD PEVEQVSGRG 300
LPDDHAGPIR VVNIEGVDSN MCCGTHVSNL SDLQVIKILG TEKGKKNRTN LIFLSGNRVL 360
KWMERSHGTE KALTALLKCG AEDHVEAVKK LQNSTKILQK NNLNLLRDLA VHIAHSLRNS 420
PDWGGVVILH RKEGDSEFMN IIANEIGSEE TLLFLTVGDE KGGGLFLLAG PPASVETLGP 480
RVAEVLEGKG AGKKGRFQGK ATKMSRRMEA QALLQDYIST QSAKE 525 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. GO:0004813; F:alanine-tRNA ligase activity; IEA:InterPro. GO:0005524; F:ATP binding; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0003676; F:nucleic acid binding; IEA:InterPro. GO:0006419; P:alanyl-tRNA aminoacylation; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |