CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-000268
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane gamma-carboxyglutamic acid protein 1 
Protein Synonyms/Alias
 Proline-rich gamma-carboxyglutamic acid protein 1; Proline-rich Gla protein 1 
Gene Name
 PRRG1 
Gene Synonyms/Alias
 PRGP1; TMG1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
10RVFLTGEKANSILKRubiquitination[1]
66EFWSTYTKAQQGESNubiquitination[1]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473
Functional Description
  
Sequence Annotation
 DOMAIN 21 66 Gla.
 DISULFID 37 42 By similarity.  
Keyword
 Alternative splicing; Complete proteome; Disulfide bond; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 218 AA 
Protein Sequence
MGRVFLTGEK ANSILKRYPR ANGFFEEIRQ GNIERECKEE FCTFEEAREA FENNEKTKEF 60
WSTYTKAQQG ESNRGSDWFQ FYLTFPLIFG LFIILLVIFL IWRCFLRNKT RRQTVTEGHI 120
PFPQHLNIIT PPPPPDEVFD SSGLSPGFLG YVVGRSDSVS TRLSNCDPPP TYEEATGQVN 180
LQRSETEPHL DPPPEYEDIV NSNSASAIPM VPVVTTIK 218 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:InterPro.
 GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR017857; Coagulation_fac_subgr_Gla_dom.
 IPR000294; GLA_domain. 
Pfam
 PF00594; Gla 
SMART
 SM00069; GLA 
PROSITE
 PS00011; GLA_1
 PS50998; GLA_2 
PRINTS
 PR00001; GLABLOOD.